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Letters |15 December 1993

Fibrinogen and Cardiovascular Risk

Edzard Ernst, MD; Karl Ludwig Resch, MD

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IN RESPONSE:
Several points raised in this letter are relevant. The pharmacologic alteration of fibrinogen seems a grossly under-researched area. Many drugs influence the alteration but often it is difficult to determine if it results from the drug's effect on a given disorder or is a direct effect of the drug itself.
That fibrinogen levels increase in intermittent claudication has been observed repeatedly. Recently, Lowe and coworkers [1] reported epidemiologic data showing that the increase is independently associated with peripheral arterial narrowing. Thus, a prognostic relevance of fibrinogen in peripheral arterial occlusive disease comes as little surprise, particularly when considering...
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Ernst E, Resch KL. Fibrinogen and Cardiovascular Risk. Ann Intern Med. 1993;119:1222–1223. doi: 10.7326/0003-4819-119-12-199312150-00016

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Published: Ann Intern Med. 1993;119(12):1222-1223.

DOI: 10.7326/0003-4819-119-12-199312150-00016

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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