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Letters |15 December 1993

Does Race Predispose to Angiotensin-Associated Angioneurotic Edema?

Nancy J. Brown, MD; John H. Nadeau, MD

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TO THE EDITOR:
Since the report by Wilkin and colleagues [1] of angioneurotic edema in two patients receiving captopril, many other cases associated with angiotensin- onverting enzyme (ACE) inhibitor therapy have been recognized; the incidence has been estimated to be 0.1% to 0.2% [2]. We have recently observed a higher-than-expected incidence in black patients. We examined the literature on ACE inhibitor-associated angioneurotic edema to determine whether others had noted such a trend. We reviewed 38 articles reporting cases of ACE inhibitor-associated angioneurotic edema since 1980. In 18 articles, patient race was reported for at least one case. Fifty-two of...
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Brown NJ, Nadeau JH. Does Race Predispose to Angiotensin-Associated Angioneurotic Edema?. Ann Intern Med. 1993;119:1224. doi: https://doi.org/10.7326/0003-4819-119-12-199312150-00020

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Published: Ann Intern Med. 1993;119(12):1224.

DOI: 10.7326/0003-4819-119-12-199312150-00020

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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