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The Literature of Medicine |15 January 1994

Reviews and Notes: Hematology: Sickle Cell Disease; and Sickle Cell Disease: Pathophysiology, Diagnosis, and Management

Daniel Brookoff, MD

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Copyright ©2004 by the American College of Physicians
2004
  • University of Tennessee College of Medicine, Memphis, TN 38103
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Sickle Cell Disease
Second edition. Graham R. Serjeant. 631 pages. Oxford: Oxford University Press; 1992. $59.00.
Sickle Cell Disease: Pathophysiology, Diagnosis, and Management
Vipul N. Mankad and R. Blaine Moore; eds. Westport, Connecticut: Praeger; 1992. $79.95.
Sickle cell disease has been both a triumph and a tragedy for American medicine. Scientific investigations into sickle cell disease ushered in the age of molecular medicine. At the same time, the history of sickle cell disease is also remarkable for the thousands of American children who, over the course of 300 years, died without notice from a disease that remained “undiscovered.” The paradox holds to this day, when most of my medical students can describe in frightening detail the genetic abnormality that gives rise to sickle cell disease, but few know how to care for the patients.
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Brookoff D. Reviews and Notes: Hematology: Sickle Cell Disease; and Sickle Cell Disease: Pathophysiology, Diagnosis, and Management. Ann Intern Med. 1994;120:174. doi: 10.7326/0003-4819-120-2-199401150-00035

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Published: Ann Intern Med. 1994;120(2):174.

DOI: 10.7326/0003-4819-120-2-199401150-00035

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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