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Letters |15 July 1994

Controversy over Sclerotherapy for Malignant Pleural Effusions

Leigh M. Vaughan, PharmD; Steven A. Sahn, MD

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The 1993 retrospective review in 21 patients mentioned by Fuller [1] that showed a complete response of 88% after 1 month with the use of 500 mg of intrapleural doxycycline was not available when our review was done. We agree that the issues raised by Drs. Fuller and Ruckdeschel concerning first-dose efficacy, length of hospital stay, and total costs require further study; however, we disagree that sufficient comparative data exist to state that bleomycin is more efficacious and cost-effective than doxycycline, particularly because higher doxycycline doses may have produced different results [2, 3]. It is hoped that...
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Vaughan LM, Sahn SA. Controversy over Sclerotherapy for Malignant Pleural Effusions. Ann Intern Med. 1994;121:150–151. doi: 10.7326/0003-4819-121-2-199407150-00022

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Published: Ann Intern Med. 1994;121(2):150-151.

DOI: 10.7326/0003-4819-121-2-199407150-00022

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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