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Letters |15 October 1994

Calcium Channel Antagonists and Gingival Hyperplasia

Ruth Steele, PharmD; Arthur A. Schuna, MD; Ronald Schreiber, MD

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Drs. Mathis and Scheetz raise some interesting questions regarding the dosage form of calcium antagonist and gingival hyperplasia. Because most of our patients received sustained-release preparations of calcium antagonists, we could not do a subgroup analysis with adequate numbers of patients receiving prompt-release dosage forms to do statistical comparisons. We did not assess blood levels or compliance in this prevalence survey; however, previous reports found no relation between the dosage of the calcium antagonist and the development of gingival hyperplasia [1, 2]. We found no statistical differences in age between patients with and without hyperplasia. Our patient population did not allow us to compare prevalence data by race or sex.
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Steele R, Schuna AA, Schreiber R. Calcium Channel Antagonists and Gingival Hyperplasia. Ann Intern Med. ;121:624–625. doi: 10.7326/0003-4819-121-8-199410150-00021

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Published: Ann Intern Med. 1994;121(8):624-625.

DOI: 10.7326/0003-4819-121-8-199410150-00021

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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