Skip Navigation
Menu
Editorials |1 February 1995

Clinical Research in the Acquired Immunodeficiency Syndrome

William G. Powderly, MD, FRCPI

FULL TEXT
Anniversaries tend to be occasions for reflection, for review of past accomplishments and disappointments, and for renewal of aspirations. Therefore, it is not surprising that approximately 10 years after the discovery that the human immunodeficiency virus (HIV) causes the acquired immunodeficiency syndrome (AIDS), much discussion of the progress made in AIDS research has taken place and many proposals to completely overhaul our approach to this problem have been made [1].
Clearly, this is not a time for celebration. That the progress made to date has been insufficient is plainly evident in most of our hospitals every day. The acquired immunodeficiency syndrome continues to take an unrelenting toll on our patients and our society; it is now the leading cause of death in the United States for men between the ages of 25 and 44 years, and will almost certainly achieve that unwelcome distinction for women of the same age by the end of the decade [2].
However, it is worth taking stock of where we were in 1984 to put into perspective what has been achieved and what still needs to be done. Patients with AIDS live longer in 1994 than they did in 1984—almost three times as long—and although the cause of this increased survival is not totally apparent, it is largely due to improved therapy and prevention of opportunistic processes [3]. In 1984, no antiretroviral drugs were available. In 1994, we have agents that, when used as monotherapy, slow the progress of disease; when used...
FULL TEXT
PDF
Not Available
Citations
Citation

Powderly WG. Clinical Research in the Acquired Immunodeficiency Syndrome. Ann Intern Med. 1995;122:232–233. doi: https://doi.org/10.7326/0003-4819-122-3-199502010-00014

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 1995;122(3):232-233.

DOI: 10.7326/0003-4819-122-3-199502010-00014

1 Citations

Related Articles
Gastrointestinal Cytomegalovirus Disease
Annals of Internal Medicine; 119 (9): 924-935
Primary Cutaneous Tuberculosis after a Needlestick Injury from a Patient with AIDS and Undiagnosed Tuberculosis
Annals of Internal Medicine; 119 (7_Part_1): 594-595
Delayed-Type Hypersensitivity Skin Testing Predicts Progression to AIDS in HIV-infected Patients
Annals of Internal Medicine; 119 (3): 177-184
Chronic Diarrhea and Malabsorption Associated with Enteropathogenic Bacterial Infection in a Patient with AIDS
Annals of Internal Medicine; 119 (2): 127-128
View MoreView Less

Related Topics
HIV
Infectious Disease

HIV, Infectious Disease.

PubMed Articles
[Public health and eradication of infection by the Human Immunodeficiency Virus].
Rev Esp Salud Publica 2019;93():.
Cardiovascular manifestations of people living with HIV/AIDS: Report from a hot spot in eastern India.
Indian Heart J ;71(4):338-343.
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×