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Letters |15 February 1995

Aseptic Meningitis and Intravenous Immunoglobulin Therapy

Yadollah Harati; Aziz Taher Shaibani

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TO THE EDITOR:
Sekul and colleagues [1] described the association between aseptic meningitis and high-dose intravenous immunoglobulin and reported that 11% (6 of 54) of their patients developed aseptic meningitis after receiving intravenous immunoglobulin. However, they did not mention the specific immunoglobulin product or products they used, although they asserted that a change in the “commercial lot or product, for unknown reasons, was effective in preventing the recurrence of aseptic meningitis”.
Considering the high incidence of aseptic meningitis reported by these authors and the fact that different intravenous immunoglobulin products vary in the type and amount of the vehicle and in their immunoglobulin contents, it would be useful if the authors provided readers with the brand name of the product or products used in their patients.
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Harati Y, Shaibani AT. Aseptic Meningitis and Intravenous Immunoglobulin Therapy. Ann Intern Med. ;122:316–317. doi: 10.7326/0003-4819-122-4-199502150-00019

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Published: Ann Intern Med. 1995;122(4):316-317.

DOI: 10.7326/0003-4819-122-4-199502150-00019

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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