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Letters |1 March 1995

Nonsteroidal Anti-inflammatory Drugs and High Blood Pressure

Ken Radack

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Author, Article, and Disclosure Information
  • University of Cincinnati Medical Center, Cincinnati, OH 645267-0535. Princess Alexandra Hospital, Woolloongabba, 4102 Queensland, Australia.
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TO THE EDITOR:
I was surprised by the recent meta-analysis by Johnson and colleagues [1] on nonsteroidal anti-inflammatory drugs (NSAIDs) and blood pressure. Several important aspects of the validity and generalizability of the study need serious attention before readers can apply the information.
First, the “methodologic rigor” for individual studies was not very rigorous. For example, the study by Radack and colleagues [2] included 41 patients, not 30. The patients were predominantly black women (21 of 41 patients), not white (their Appendix Table 1), and the male-to-female ratio was 15:26, not 7:19 (their Appendix Table 1). We highlighted these differences...
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Radack K. Nonsteroidal Anti-inflammatory Drugs and High Blood Pressure. Ann Intern Med. 1995;122:397. doi: 10.7326/0003-4819-122-5-199503010-00027

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Published: Ann Intern Med. 1995;122(5):397.

DOI: 10.7326/0003-4819-122-5-199503010-00027

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