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Letters |15 August 1995

Diabetes Mellitus and Interferon-α Therapy

Masami Murakami; Tokuji Iriuchijima; Masatomo Mori

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Author, Article, and Disclosure Information
  • Gunma University School of Medicine; Maebashi 371; Japan
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TO THE EDITOR:
Autoimmune mechanisms are involved in the pathogenesis of type 1 diabetes mellitus [1]. Organ- or non-organ-specific autoimmune events have been reported to occur after interferon therapy [2]. We report a case of type 1 diabetes mellitus associated with ketoacidosis during interferon-α therapy.
A 66-year-old Japanese man (body mass index, 24.2 kg/m2) had a left nephrectomy for renal cell carcinoma on 22 June 1993. He had no overt or family history of diabetes mellitus. One month earlier, his fasting and postprandial blood glucose levels were 5.7 mmol/L and 6.5 mmol/L, respectively. He began receiving...
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Murakami M, Iriuchijima T, Mori M. Diabetes Mellitus and Interferon-α Therapy. Ann Intern Med. 1995;123:318. doi: 10.7326/0003-4819-123-4-199508150-00024

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Published: Ann Intern Med. 1995;123(4):318.

DOI: 10.7326/0003-4819-123-4-199508150-00024

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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