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Letters |1 September 1995

Minocycline in Rheumatoid Arthritis

Richard Meehan, MD

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Author, Article, and Disclosure Information
  • University of Colorado Health Sciences Center; Denver, CO 80262
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TO THE EDITOR:
The extremely well-designed study by Tilley and colleagues [1] has many features that should allow the authors to detect a statistically significant difference between placebo and drug treatment groups. The authors successfully showed a benefit (albeit small [54% compared with 39%]) in the drug treatment group. However, they did not report additional specific information on the corticosteroid dose and the specific nonsteroidal agent received in both groups or on the changes that could have developed between the control and treatment groups over time. Specifically, was there a statistically significant difference between objective variables such as joint swelling...
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Meehan R. Minocycline in Rheumatoid Arthritis. Ann Intern Med. 1995;123:391. doi: 10.7326/0003-4819-123-5-199509010-00018

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Published: Ann Intern Med. 1995;123(5):391.

DOI: 10.7326/0003-4819-123-5-199509010-00018

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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