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Letters |15 September 1995

Host-Directed Therapy for AIDS

Michael M. Lederman, MD

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  • Case Western Reserve University; Cleveland, OH 44106
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Stricker and Goldberg suggest that DNCB is used by thousands of HIV-infected patients around the world at a cost of pennies a week [1]. Although the cash outlay for DNCB is modest, the actual cost of this therapy may be substantially greater. The clinical value of DNCB is currently uncertain. Several uncontrolled studies have suggested that some patients treated with DNCB may experience increases in the number of circulating CD8+ lymphocytes; in some instances, increases in the number of CD56+ lymphocytes (cells with a natural killer phenotype) were also seen [2, 3]. These observations must be...
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Lederman MM. Host-Directed Therapy for AIDS. Ann Intern Med. 1995;123:472. doi: 10.7326/0003-4819-123-6-199509150-00020

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Published: Ann Intern Med. 1995;123(6):472.

DOI: 10.7326/0003-4819-123-6-199509150-00020

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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