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Letters |1 January 1996

Increase in Serum Free Thyroxine Levels Related to Intravenous Heparin Treatment

Rita Jain, MD; Harry L. Uy, MD

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Copyright ©2004 by the American College of Physicians
2004
  • University of Texas Health Science Center at San Antonio; San Antonio, TX 78284
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TO THE EDITOR:
Heparin has been shown to affect thyroid function test results [1, 2]. Because heparin is now commonly used to treat patients with unstable angina or atrial arrhythmias, physicians should be aware of this interaction. We describe a patient with a heparin-induced increase in the serum free thyroxine level as measured by direct equilibrium dialysis and a one-step free thyroxine immunoassay.
A 62-year-old woman with diabetes mellitus, hypertriglyceridemia, and coronary artery disease presented with unstable angina. On physical examination she appeared to be euthyroid, with no palpable thyroid nodules or goiter. She began receiving intravenous heparin, and...
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Jain R, Uy HL. Increase in Serum Free Thyroxine Levels Related to Intravenous Heparin Treatment. Ann Intern Med. 1996;124:74–75. doi: 10.7326/0003-4819-124-1_Part_1-199601010-00022

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Published: Ann Intern Med. 1996;124(1_Part_1):74-75.

DOI: 10.7326/0003-4819-124-1_Part_1-199601010-00022

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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