Diuretics and Sudden Cardiac Death

Angeli R. Maun; John Concato

doi:10.7326/0003-4819-125-4-199608150-00029

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Letters |15 August 1996

Diuretics and Sudden Cardiac Death

Angeli R. Maun, MD; John Concato, MD, MS, MPH

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TO THE EDITOR:

Hoes and colleagues [1] concluded that “the use of non-potassium-sparing diuretics and β-blockers is associated with an increased risk for sudden cardiac death.” Their data, however, do not fully support (or at least explain) this conclusion. First, none of the “bivariate” associations (their Table 2 between exposure to various categories of diuretic or β-blocker use and outcome as case–control status were clinically or statistically significant. For example, 21.8% of case-patients [n = 56] were taking non-potassium-sparing diuretics, regardless of β-blocker use, compared with 17.9% of controls (n = 46) (odds ratio, 1.5 [95% CI, 0.9...

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Letters |15 August 1996

Diuretics and Sudden Cardiac Death

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Letters |15 August 1996

Diuretics and Sudden Cardiac Death

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