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Letters |15 September 1996

Non-Insulin-Dependent Diabetes Mellitus Developing during Interferon-α Therapy for Chronic Hepatitis C

Pierre Chedin, MD; Juliette Cahen-Varsaux, MD; Nathalie Boyer, MD

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Author, Article, and Disclosure Information
  • Victor Dupony Hospital, 95107 Argenteuil, France Beaujon Hospital, 92118 Clichy, France
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TO THE EDITOR:
Development of non–insulin-dependent (autoimmune) diabetes mellitus has been suggested in patients treated with interferon-α [1-3]. We describe a patient who developed this disease with no evidence of an immune process while receiving interferon-α for hepatitis C.
A 50-year-old man was referred to us because of chronic active hepatitis C. His cousin had insulin-dependent diabetes, but no family member had a history of non–insulin-dependent diabetes. Recombinant interferon-α was started at a dose of 32 million U three times a week. Before therapy, the patient had glucose intolerance. After 1 week of treatment, his fasting plasma blood glucose...
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Chedin P, Cahen-Varsaux J, Boyer N. Non-Insulin-Dependent Diabetes Mellitus Developing during Interferon-α Therapy for Chronic Hepatitis C. Ann Intern Med. 1996;125:521. doi: https://doi.org/10.7326/0003-4819-125-6-199609150-00035

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Published: Ann Intern Med. 1996;125(6):521.

DOI: 10.7326/0003-4819-125-6-199609150-00035

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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