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Letters |15 October 1996

Bell Palsy and Herpes Simplex Virus

P.P. Devriese, MD, PhD

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  • Academic Medical Center, 1105 AZ Amsterdam, the Netherlands
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TO THE EDITOR:
Murakami and colleagues [1] used polymerase chain reaction to detect herpes simplex virus type 1 (HSV-1) DNA in patients with Bell palsy and to detect varicella-zoster DNA in patients with the Ramsay Hunt syndrome. Their report is an important contribution to the etiology of these diseases [2].
Contrary to the authors' statement in the introduction of their article, I suggested ischemia not as a cause of Bell palsy but as a factor in the pathogenesis of the paralysis. Inflammation of the facial nerve caused by reactivation of the virus may provoke edema and, as a result, compress the nerve inside the nerve sheath. I demonstrated that in cats, the facial nerve in the facial canal can be paralyzed from within by increasing pressure inside the nerve to supradiastolic and suprasystolic levels [3].
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Devriese P. Bell Palsy and Herpes Simplex Virus. Ann Intern Med. 1996;125:698. doi: 10.7326/0003-4819-125-8-199610150-00023

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Published: Ann Intern Med. 1996;125(8):698.

DOI: 10.7326/0003-4819-125-8-199610150-00023

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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