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Letters |1 June 1997

Hypolipidemic Drugs in Coronary Artery Disease

Richard C. Pasternak, MD; Frank M. Sacks, MD

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  • Harvard Medical School, Boston, MA 02114
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IN RESPONSE:
We appreciate the comments of Drs. Isley and Bittar. Both are correct in pointing out an error in our citation of the work of Stein and colleagues [1], which, in fact, compared simvastatin with cholestyramine and did not study the combination of the two drugs. We regret the misunderstanding.
With regard to Dr. Isley's other comments, we recognize that simvastatin is, in general, more potent than the statins that we had available at the time our study began. However, at the 40-mg pravastatin dose, the incremental effect of 40 mg of simvastatin on LDL cholesterol levels would...
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Pasternak RC, Sacks FM. Hypolipidemic Drugs in Coronary Artery Disease. Ann Intern Med. 1997;126:917. doi: 10.7326/0003-4819-126-11-199706010-00020

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Published: Ann Intern Med. 1997;126(11):917.

DOI: 10.7326/0003-4819-126-11-199706010-00020

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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