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Letters |15 March 1998

Monitoring Warfarin Therapy in Patients with Lupus Anticoagulants

Arumugam Manoharan, MD

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  • St. George Hospital; Kogarah, Sydney, Australia
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TO THE EDITOR:
Moll and Ortel [1] raise an important clinical management issue: Use of international normalized ratios may not be a reliable way to monitor warfarin therapy in some patients with lupus anticoagulants. In a report published 20 years ago [2], my colleagues and I documented the use of the “Thrombotest” [3] in a patient with lupus anticoagulant. Because this test measured overall clotting activity and the result was expressed as percentage of activity [4], we thought that it was better for monitoring oral anticoagulant therapy than the conventional prothrombin time in patients with lupus anticoagulants. Can...
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Manoharan A. Monitoring Warfarin Therapy in Patients with Lupus Anticoagulants. Ann Intern Med. 1998;128:504. doi: 10.7326/0003-4819-128-6-199803150-00016

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Published: Ann Intern Med. 1998;128(6):504.

DOI: 10.7326/0003-4819-128-6-199803150-00016

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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