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Letters |1 April 1998

Positive-Pressure Ventilation in Amyotrophic Lateral Sclerosis

Loutfi S. Aboussouan, MD; Saeed U. Khan, MD; Hiroshi Mitsumoto, MD

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  • Wayne State University School of Medicine; Detroit, MI 48201 Cleveland Clinic Foundation; Cleveland, OH 44195
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We agree that noninvasive positive-pressure ventilation should not be restricted to nighttime. Although we emphasized nocturnal use, we also encouraged daytime use. However, tolerance of this treatment was strictly defined as the ability to sleep nightly for at least 4 consecutive hours with the device, regardless of daytime use. We did use other interfaces, including mouth pieces for daytime ventilation. Every attempt was made to control mucus plugging and secretions by using suction devices, medications, and assisted coughing. Mechanical insufflation-exsufflation was used, but only when it became available at the end of our study.
In that context, our...
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Aboussouan LS, Khan SU, Mitsumoto H. Positive-Pressure Ventilation in Amyotrophic Lateral Sclerosis. Ann Intern Med. 1998;128:602. doi: https://doi.org/10.7326/0003-4819-128-7-199804010-00026

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Published: Ann Intern Med. 1998;128(7):602.

DOI: 10.7326/0003-4819-128-7-199804010-00026

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