Kent E. Kester, MD; George W. Turiansky, MD; Peter L. McEvoy, MD
In AIDS, nodular skin disease can result from various causes.
To report a new manifestation of microsporidial infection presenting as nodular skin disease with underlying osteomyelitis.
Tertiary-care military medical center in Washington, D.C.
A 36-year-old woman with late-stage AIDS who presented with disseminated, nodular cutaneous lesions and underlying osteomyelitis.
Disseminated microsporidial infection with an Encephalitozoon-like species was diagnosed by electron microscopic examination of material obtained from the skin lesions.
The patient received long-term oral clindamycin therapy, which cured her disseminated infection.
Microsporidia can cause disseminated cutaneous infections in AIDS patients. The response of this patient to long-term clindamycin therapy merits further evaluation.
Kester KE, Turiansky GW, McEvoy PL. Nodular Cutaneous Microsporidiosis in a Patient with AIDS and Successful Treatment with Long-Term Oral Clindamycin Therapy. Ann Intern Med. 1998;128:911–914. doi: https://doi.org/10.7326/0003-4819-128-11-199806010-00009
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Published: Ann Intern Med. 1998;128(11):911-914.
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