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Letters |4 April 2000

Medical Management of Aldosterone-Producing Adenomas

Nor N. Chan, MB, ChB, MRCP

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Author, Article, and Disclosure Information
  • University College London; London, United Kingdom (Chan)
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TO THE EDITOR:
Ghose and colleagues (1) showed that long-term medical management (5 to 17 years) is a reasonable option for aldosterone-producing adenomas diagnosed by standard biochemistry and computed tomography in terms of blood pressure control and normalization of serum potassium levels in patients who decline or are unfit for surgery. However, I have concerns about the diagnostic accuracy in their cohort of patients. The use of computed tomography alone without adrenal venous sampling is often inadequate in differentiating between aldosterone-producing adenomas and adrenocortical hyperplasia (2, 3), the two major causes of primary hyperaldosteronism. In a series of hypertensive...
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Chan NN. Medical Management of Aldosterone-Producing Adenomas. Ann Intern Med. 2000;132:594. doi: 10.7326/0003-4819-132-7-200004040-00022

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Published: Ann Intern Med. 2000;132(7):594.

DOI: 10.7326/0003-4819-132-7-200004040-00022

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2000 American College of Physicians
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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