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Letters |19 June 2001

Tamoxifen-Induced Total Alopecia

Fabio Puglisi, MD; Giuseppe Aprile, MD; Alberto Sobrero, MD

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Author, Article, and Disclosure Information
  • Policlinico Universitario; I-33100 Udine, Italy (Puglisi, Aprile, Sobrero)
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TO THE EDITOR:
We describe a case of alopecia in a 53-year-old woman receiving the antiestrogen tamoxifen (20 mg/d) for biopsy-proven, estrogen receptor–positive metastases to the supraclavicular lymph nodes. The patient was taking no other medications.
Mild alopecia occurred after 3 months, with hair loss in the frontal (Figure, top) and nuchal areas. The patient continued tamoxifen treatment, although alopecia progressively worsened. At the most recent follow-up visit (13 months after tamoxifen therapy was started), the patient wore a wig to mask complete hair loss (Figure, bottom). Hair distribution was normal in other areas...
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Puglisi F, Aprile G, Sobrero A. Tamoxifen-Induced Total Alopecia. Ann Intern Med. 2001;134:1154–1155. doi: 10.7326/0003-4819-134-12-200106190-00029

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Published: Ann Intern Med. 2001;134(12):1154-1155.

DOI: 10.7326/0003-4819-134-12-200106190-00029

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2001 American College of Physicians
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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