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Letters |4 September 2001

Periodic Liver Biopsy for Mild Hepatitis C

Barry Kisloff, MD

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
  • Alliance Medical; Pittsburgh, PA 15232 (Kisloff)
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TO THE EDITOR:
The report by Wong and Koff (1), which advocates initial interferon-ribavirin therapy for mild chronic hepatitis C, seems flawed in several ways. First, it ignores reports (2, 3) that predict a significantly lower rate of progression to cirrhosis from chronic hepatitis C than the 27.5% or even 9.5% used in their study. Inclusion of these data would probably change the outcomes reported. The failure to even mention these and other similar reports showing a more favorable outcome of chronic hepatitis C is troubling. Second, in calculating costs for the group of patients with mild hepatitis, more...
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Kisloff B. Periodic Liver Biopsy for Mild Hepatitis C. Ann Intern Med. 2001;135:381. doi: 10.7326/0003-4819-135-5-200109040-00019

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Published: Ann Intern Med. 2001;135(5):381.

DOI: 10.7326/0003-4819-135-5-200109040-00019

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2001 American College of Physicians
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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