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Letters |15 January 2002

Prevention of Antibiotic Resistance in Hospitals

Marin Kollef, MD

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Author, Article, and Disclosure Information
  • Washington University School of Medicine; Barnes-Jewish Hospital; St. Louis, MO 63110
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IN RESPONSE:
Dr. Fraser and I agree with Dr. Johnson that patients' underlying host defenses play a very important role in determining susceptibility to infection with antibiotic-resistant microorganisms. In addition, studies attempting to define the impact of antibiotic resistance on clinical outcomes need to take severity of illness and other underlying patient characteristics into account. Only in this way can accurate estimates be made concerning the impact of antibiotic resistance on hospital mortality and other clinical outcomes. We also thank Drs. Singh and Yu for clarifying how they used the clinical pulmonary infection score in their clinical trial. More studies...
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Kollef M. Prevention of Antibiotic Resistance in Hospitals. Ann Intern Med. 2002;136:173. doi: 10.7326/0003-4819-136-2-200201150-00019

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Published: Ann Intern Med. 2002;136(2):173.

DOI: 10.7326/0003-4819-136-2-200201150-00019

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2002 American College of Physicians
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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