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Letters |20 February 2007

Hypothyroidism as a Mimic of Liver Failure in a Patient with Cirrhosis

Raed N. Khairy, MD; Kevin D. Mullen, MD

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
  • From University of Michigan Health System, Ann Arbor, Michigan, and Case Western Reserve University and MetroHealth Medical Center, Cleveland, Ohio.

    Potential Financial Conflicts of Interest: None disclosed.

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Background: Hypothyroidism is an unusual cause of ascites. Hypothyroidism may also mimic hepatic encephalopathy in patients with cirrhosis. Reversible, hypothyroidism-induced ascites and encephalopathy simulating liver failure in a patient with cirrhosis awaiting liver transplantation has not been reported.
Objective: To describe the resolution of intractable ascites and encephalopathy with treatment of hypothyroidism in a patient with cirrhosis awaiting transplantation.
Case Report: A 40-year-old woman with cirrhosis secondary to chronic hepatitis C virus infection had intractable ascites and encephalopathy. She was listed for liver transplantation at another institution. She presented for a second opinion to determine whether additional evaluation and treatment might preclude the need for transplantation.
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Khairy RN, Mullen KD. Hypothyroidism as a Mimic of Liver Failure in a Patient with Cirrhosis. Ann Intern Med. ;146:315–316. doi: 10.7326/0003-4819-146-4-200702200-00021

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Published: Ann Intern Med. 2007;146(4):315-316.

DOI: 10.7326/0003-4819-146-4-200702200-00021

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2007 American College of Physicians
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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