Skip Navigation
Menu
ACP Journal Club |20 May 2008

Testosterone supplementation did not prevent cognitive decline or increase bone mineral density in older men

Eef Hogervorst, PhD

Article, Author, and Disclosure Information
FULL TEXT
Similar to most studies investigating sex steroids and cognitive function in older men and women, the trial by Emmelot-Vonk and colleagues has some methodological shortcomings (1). Power analyses were based on an expected improvement of 6 words on the memory test, but the basis for this estimate is unclear. Clinicians and patients often claim memory improvement after testosterone treatment, and animal and cell studies also show beneficial effects on brain tissue (1). In this study, hormone-related quality-of-life measures, but not other quality of life or mood scales, improved after administration of testosterone, which has been reputed to mediate...
FULL TEXT
PDF
Not Available
Citations
Citation

Hogervorst E. Testosterone supplementation did not prevent cognitive decline or increase bone mineral density in older men. Ann Intern Med. 2008;148:JC3–4. doi: https://doi.org/10.7326/0003-4819-148-10-200805200-02004

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 2008;148(10):JC3-4.

DOI: 10.7326/0003-4819-148-10-200805200-02004

0 Citations

Related Articles
Association of Hypogonadism and Estradiol Levels with Bone Mineral Density in Elderly Men from the Framingham Study
Annals of Internal Medicine; 133 (12): 951-963
Levels of Testosterone and Estrogen and Bone Density in Elderly Men
Annals of Internal Medicine; 133 (12): S62
Inability to correctly identify year or month was accurate for detecting cognitive impairment in older patients
Annals of Internal Medicine; 155 (6): JC3-9
Cognitive Impairment without Dementia in Older Adults
Annals of Internal Medicine; 148 (6): I-53
View MoreView Less

Journal Club
Inability to correctly identify year or month was accurate for detecting cognitive impairment in older patients
Annals of Internal Medicine; 155 (6): JC3-9
Review: In adults with normal cognition or MCI, drugs do not prevent or delay cognitive decline
Annals of Internal Medicine; 168 (8): JC39
In older men with low testosterone levels and age-associated memory impairment, testosterone did not improve memory
Annals of Internal Medicine; 166 (10): JC56
Testosterone gel improved sexual function, but not walk distance or fatigue, in older men with low testosterone
Annals of Internal Medicine; 164 (10): JC56
View MoreView Less

Related Point of Care
Fall Prevention in Community-Dwelling Older Adults
Annals of Internal Medicine; 169 (11): ITC81-ITC96
View MoreView Less

Related Topics
Endocrine and Metabolism
Geriatric Medicine
Metabolic Bone Disorders

Endocrine and Metabolism, Geriatric Medicine, Metabolic Bone Disorders.

PubMed Articles
[Recommendations for the Detection and Specification of Perioperative Neurocognitive Disorders].
Anasthesiol Intensivmed Notfallmed Schmerzther 2019;54(11-12):652-667.
Increased Prevalence of Severe Obesity and Related Comorbidities among Patients Referred to a Pediatric Obesity Clinic during the Last Decade.
Horm Res Paediatr 2019.
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×