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ACP Journal Club |16 December 2008

Benefits of tight blood pressure control to prevent diabetes complications were not sustained

Eoin P. O’Sullivan, MD; Sean F. Dinneen, MD

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Holman RR, Paul SK, Bethel MA, Neil HA, Matthews DR. Long-term follow-up after tight control of blood pressure in type 2 diabetes. N Engl J Med. 2008;359:1565-76. 18784091

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Endocrinology:

See alsoBenefits of early intensive glucose control in preventing diabetes-related complications were sustained for up to 10 years
The UKPDS has contributed hugely to our understanding of the benefits of intensive glycemic and blood pressure control on clinically relevant outcomes in type 2 diabetes. Tight glycemic control was shown to reduce microvascular complications, although the reduction in macrovascular events failed to achieve statistical significance (1). Tight blood pressure...
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O’Sullivan EP, Dinneen SF. Benefits of tight blood pressure control to prevent diabetes complications were not sustained. Ann Intern Med. 2008;149:JC6–5. doi: 10.7326/0003-4819-149-12-200812160-02005

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Published: Ann Intern Med. 2008;149(12):JC6-5.

DOI: 10.7326/0003-4819-149-12-200812160-02005

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