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ACP Journal Club |16 December 2008

A single measure of urinary neutrophil gelatinase–associated lipocalin was accurate for diagnosing acute kidney injury

Anna Mathew, MD; Amit X. Garg, MD

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Nickolas TL, O′Rourke MJ, Yang J, et al. Sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury. Ann Intern Med. 2008;148:810-9. 18519927

Emergency Med:

Hospitalists:

Nephrology:

AKI occurs frequently in the hospital setting and affects morbidity, mortality, and resource use, regardless of country, etiology, setting, or definition. In current practice, AKI is identified by a large, persistent increase in serum creatinine levels. However, physicians want to diagnose AKI as early as possible, and the serum creatinine increase happens days after AKI occurs. Early changes in serum creatinine are not particularly...
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Mathew A, Garg AX. A single measure of urinary neutrophil gelatinase–associated lipocalin was accurate for diagnosing acute kidney injury. Ann Intern Med. 2008;149:JC6–13. doi: 10.7326/0003-4819-149-12-200812160-02013

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Published: Ann Intern Med. 2008;149(12):JC6-13.

DOI: 10.7326/0003-4819-149-12-200812160-02013

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