Skip Navigation
Menu
ACP Journal Club |21 April 2009

Review: Brand-name drugs are not more effective than generic versions for treating cardiovascular disease

Braden Manns, MD

Article, Author, and Disclosure Information
FULL TEXT
Kesselheim AS, Misono AS, Lee JL, et al. Clinical equivalence of generic and brand-name drugs used in cardiovascular disease: a systematic review and meta-analysis. JAMA. 2008;300:2514-26. 19050195

GIM/FP/GP:

Cardiology:

Hematol/Thrombo:

Kesselheim and colleagues have conducted a comprehensive review of studies comparing the effectiveness of generic and brand-name drugs. As noted in the editorials discussed in this article, many physicians are uncomfortable with the notion of generic substitution, possibly due to anecdotal experience or a perception that the physician’s direction has been subverted. However, generic drugs are typically more than 30% less expensive, which can be important to cash-strapped health care...
FULL TEXT
PDF
Not Available
Citations
Citation

Manns B. Review: Brand-name drugs are not more effective than generic versions for treating cardiovascular disease. Ann Intern Med. 2009;150:JC4–6. doi: https://doi.org/10.7326/0003-4819-150-8-200904210-02006

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 2009;150(8):JC4-6.

DOI: 10.7326/0003-4819-150-8-200904210-02006

0 Citations

Related Articles
Statins and Multiple Noncardiovascular Outcomes: Umbrella Review of Meta-analyses of Observational Studies and Randomized Controlled Trials
Annals of Internal Medicine; 169 (8): 543-553
Review: Folic acid may reduce risk for CVD and stroke, and B-vitamin complex may reduce risk for stroke
Annals of Internal Medicine; 169 (8): JC44
Clonal Hematopoiesis Confers Predisposition to Both Cardiovascular Disease and Cancer: A Newly Recognized Link Between Two Major Killers
Annals of Internal Medicine; 169 (2): 116-117
Clinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk
Annals of Internal Medicine; 169 (1): 20-29
View MoreView Less

Journal Club
Review: Folic acid may reduce risk for CVD and stroke, and B-vitamin complex may reduce risk for stroke
Annals of Internal Medicine; 169 (8): JC44
In type 2 diabetes with CVD and kidney disease, empagliflozin reduced mortality and hospitalization
Annals of Internal Medicine; 168 (10): JC52
In stable CVD, rivaroxaban plus aspirin reduced CV events and increased bleeding compared with aspirin alone
Annals of Internal Medicine; 167 (10): JC52
Evolocumab reduced CV events in patients with atherosclerotic CV disease taking high- or moderate-intensity statins
Annals of Internal Medicine; 167 (2): JC7
View MoreView Less

Related Topics
Cardiology

Cardiology.

PubMed Articles
Screening active ingredients of rosemary based on spectrum-effect relationships between UPLC fingerprint and vasorelaxant activity using three chemometrics.
J Chromatogr B Analyt Technol Biomed Life Sci 2019;
Examining the impact of data quality and completeness of electronic health records on predictions of patients' risks of cardiovascular disease.
Int J Med Inform 2019;
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×