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Letters |18 January 2011

The Effect of Funding Source on Outcome Reporting Among Drug Trials

Erick H. Turner, MD

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Author, Article, and Disclosure Information
Potential Conflicts of Interest: Dr. Turner was on speakers' bureaus for AstraZeneca, Bristol-Myers Squibb, and Eli Lilly; these activities ceased 5 years ago.
  • From Oregon Health & Science University, Portland, OR 97239.
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Potential Conflicts of Interest: Dr. Turner was on speakers' bureaus for AstraZeneca, Bristol-Myers Squibb, and Eli Lilly; these activities ceased 5 years ago.
TO THE EDITOR:
I read Bourgeois and colleagues' recent article (1) with interest, and I agree with the point made in the rapid responses on www.annals.org about the importance of the differences in sample size. Although this confounding variable was not mentioned in the article's Discussion section, it could have played a major role in generating the outcome observed.
As can be seen in the authors' Table 1, the median final sample size for the industry-sponsored trials...
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Turner EH. The Effect of Funding Source on Outcome Reporting Among Drug Trials. Ann Intern Med. 2011;154:137. doi: 10.7326/0003-4819-154-2-201101180-00018

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Published: Ann Intern Med. 2011;154(2):137.

DOI: 10.7326/0003-4819-154-2-201101180-00018

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