Skip Navigation
American College of Physicians Logo
  • Subscribe
  • Submit a Manuscript
  • Sign In
    Sign in below to access your subscription for full content
    INDIVIDUAL SIGN IN
    Sign In|Set Up Account
    You will be directed to acponline.org to register and create your Annals account
    INSTITUTIONAL SIGN IN
    Open Athens|Shibboleth|Log In
    Annals of Internal Medicine
    SUBSCRIBE
    Subscribe to Annals of Internal Medicine.
    You will be directed to acponline.org to complete your purchase.
Annals of Internal Medicine Logo Menu
  • Latest
  • Issues
  • Channels
  • CME/MOC
  • In the Clinic
  • Journal Club
  • Web Exclusives
  • Author Info
Advanced Search
  • ‹ PREV ARTICLE
  • This Issue
  • NEXT ARTICLE ›
Summaries for Patients |21 May 2013

Effect of Age, Tumor Risk, and Comorbidity on Prostate Cancer Survival Free

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.
Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians.
  • The full report is titled “Effect of Age, Tumor Risk, and Comorbidity on Competing Risks for Survival in a U.S. Population–Based Cohort of Men With Prostate Cancer.” It is in the 21 May 2013 issue of Annals of Internal Medicine (volume 158, pages 709-717). The authors are T.J. Daskivich, K.H. Fan, T. Koyama, P.C. Albertsen, M. Goodman, A.S. Hamilton, R.M. Hoffman, J.L. Stanford, A.M. Stroup, M.S. Litwin, and D.F. Penson.

×
  • ‹ PREV ARTICLE
  • This Issue
  • NEXT ARTICLE ›
Jump To
  • Full Article
  • FULL ARTICLE
  • FULL ARTICLE
    • What is the problem and what is known about it so far?
    • Why did the researchers do this particular study?
    • Who was studied?
    • How was the study done?
    • What did the researchers find?
    • What were the limitations of the study?
    • What are the implications of the study?
  • Figures
  • Tables
  • Supplements
  • Audio/Video
  • Summary for Patients
  • Clinical Slide Sets
  • CME / MOC
  • Comments
  • Twitter Link
  • Facebook Link
  • Email Link
More
  • LinkedIn Link
  • CiteULike Link

What is the problem and what is known about it so far?

It can be difficult to decide whether men diagnosed with prostate cancer will benefit from treatment because many will ultimately die of other medical issues. Knowing more about the survival of men with prostate cancer and other medical issues might help.

Why did the researchers do this particular study?

To see whether the survival of men with prostate cancer differed according to the presence and number of other medical problems.

Who was studied?

3183 men with prostate cancer that had not spread when the study began.

How was the study done?

The researchers used information that had been collected in a large study of men with prostate cancer. Within 6 months of diagnosis, the men completed a survey on which they indicated whether they had other medical problems (such as lung or heart disease). Their medical records were also reviewed to find details about the prostate cancer and its treatment. The researchers followed the men in the study and evaluated relationships among other diseases that were present; what kind of treatment was given; and whether the men died and, if so, whether they died of prostate cancer or something else.

What did the researchers find?

The greater the number of other medical problems reported on the survey, the greater the chance that the men later died of something other than prostate cancer. The increase in the chance of dying of another medical problem became greater the older the men were. For example, the chance of dying of something other than prostate cancer within 10 years was 26% for men younger than 60 years with 3 or more of the other medical problems assessed and 71% for men older than 75 years with the same number of other medical problems. Men with no or few medical problems who received aggressive prostate cancer treatment (such as surgery or radiation) seemed less likely to die of the disease than those who received less aggressive treatment (such as antihormone treatment). This was not the case in men with a greater number of other medical problems.

What were the limitations of the study?

The researchers could not confirm whether the other medical problems were actually present. The treatments that the men received were probably influenced by personal preferences and other issues that could not be measured and factored into the researchers' analyses.

What are the implications of the study?

Men with prostate cancer should discuss with their physicians whether their other medical problems are important when deciding whether they will benefit from prostate cancer treatment.

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

This feature is available only to Registered Users

Subscribe/Learn More
Submit a Comment

0 Comments

PDF
Not Available
Citations
Citation

Effect of Age, Tumor Risk, and Comorbidity on Prostate Cancer Survival. Ann Intern Med. ;158:I–11. doi: 10.7326/0003-4819-158-10-201305210-00001

Download citation file:

  • Ris (Zotero)
  • EndNote
  • BibTex
  • Medlars
  • ProCite
  • RefWorks
  • Reference Manager

© 2019

×
Permissions

Published: Ann Intern Med. 2013;158(10):I-11.

DOI: 10.7326/0003-4819-158-10-201305210-00001

0 Citations

See Also

Effect of Age, Tumor Risk, and Comorbidity on Competing Risks for Survival in a U.S. Population–Based Cohort of Men With Prostate Cancer
View MoreView Less

Related Articles

Effect of Age, Tumor Risk, and Comorbidity on Competing Risks for Survival in a U.S. Population–Based Cohort of Men With Prostate Cancer
Annals of Internal Medicine; 158 (10): 709-717
Pooled RCTs: Reanalysis accounting for screening intensity suggests that screening reduces prostate cancer mortality
Annals of Internal Medicine; 168 (2): JC5
Comparative Analysis of Biopsy Upgrading in Four Prostate Cancer Active Surveillance Cohorts
Annals of Internal Medicine; 168 (1): 1-9
Reconciling the Effects of Screening on Prostate Cancer Mortality in the ERSPC and PLCO Trials
Annals of Internal Medicine; 167 (7): 449-455
View MoreView Less

Journal Club

Pooled RCTs: Reanalysis accounting for screening intensity suggests that screening reduces prostate cancer mortality
Annals of Internal Medicine; 168 (2): JC5
Review: Metformin is linked to reduced mortality in type 2 diabetes with comorbid CKD and CHF
Annals of Internal Medicine; 166 (8): JC46
In prostate cancer, urinary and sexual function were worse with prostatectomy than active monitoring or radiotherapy
Annals of Internal Medicine; 165 (12): JC62
Radical prostatectomy reduced long-term mortality more than watchful waiting in early prostate cancer
Annals of Internal Medicine; 160 (12): JC10
View MoreView Less

Related Point of Care

Prostate Cancer
Annals of Internal Medicine; 163 (11): ITC1
View MoreView Less

Related Topics

Hematology/Oncology
Prostate Cancer

Hematology/Oncology, Prostate Cancer.

PubMed Articles

Unmet need in rheumatology: reports from the Targeted Therapies meeting 2018.
Ann Rheum Dis 2019.
Age Adjusted Charlson Comorbidity Index Strongly Influences Survival, Irrespective of Performance Status and Age, in Patients With Advanced Prostatic Cancer Treated With Enzalutamide.
Anticancer Res 2019;39(2):863-866.
View More

Results provided by: PubMed

CME/MOC Activity Requires Users to be Registered and Logged In.
Sign in below to access your subscription for full content
INDIVIDUAL SIGN IN
Sign In|Set Up Account
You will be directed to acponline.org to register and create your Annals account
Annals of Internal Medicine
CREATE YOUR FREE ACCOUNT
Create Your Free Account|Why?
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
The Comments Feature Requires Users to be Registered and Logged In.
Sign in below to access your subscription for full content
INDIVIDUAL SIGN IN
Sign In|Set Up Account
You will be directed to acponline.org to register and create your Annals account
Annals of Internal Medicine
CREATE YOUR FREE ACCOUNT
Create Your Free Account|Why?
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
link to top

Content

  • Home
  • Latest
  • Issues
  • Channels
  • CME/MOC
  • In the Clinic
  • Journal Club
  • Web Exclusives

Information For

  • Author Info
  • Reviewers
  • Press
  • Readers
  • Institutions / Libraries / Agencies
  • Advertisers

Services

  • Subscribe
  • Renew
  • Alerts
  • Current Issue RSS
  • Latest RSS
  • In the Clinic RSS
  • Reprints & Permissions
  • Contact Us
  • Help
  • About Annals
  • About Mobile
  • Patient Information
  • Teaching Tools
  • Annals in the News
  • Share Your Feedback

Awards and Cover

  • Personae (Cover Photo)
  • Junior Investigator Awards
  • Poetry Prize

Other Resources

  • ACP Online
  • Career Connection
  • ACP Advocate Blog
  • ACP Journal Wise

Follow Annals On

  • Twitter Link
  • Facebook Link
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Sign in below to access your subscription for full content
INDIVIDUAL SIGN IN
Sign In|Set Up Account
You will be directed to acponline.org to register and create your Annals account
INSTITUTIONAL SIGN IN
Open Athens|Shibboleth|Log In
Annals of Internal Medicine
PURCHASE OPTIONS
Buy This Article|Subscribe
You will be redirected to acponline.org to sign-in to Annals to complete your purchase.
CREATE YOUR FREE ACCOUNT
Create Your Free Account|Why?
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Sign in below to access your subscription for full content
INDIVIDUAL SIGN IN
Sign In|Set Up Account
You will be directed to acponline.org to register and create your Annals account
Annals of Internal Medicine
CREATE YOUR FREE ACCOUNT
Create Your Free Account|Why?
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×