The full report is titled “The Obesity Paradox in Type 2 Diabetes Mellitus: Relationship of Body Mass Index to Prognosis. A Cohort Study.” It is in the 5 May 2015 issue of Annals of Internal Medicine (volume 162, pages 610-618). The authors are P. Costanzo, J.G.F. Cleland, P. Pellicori, A.L. Clark, D. Hepburn, E.S. Kilpatrick, P. Perrone-Filardi, J. Zhang, and S.L. Atkin.
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Bangladesh Institute of Family Medicine and Research
July 31, 2015
Do not gain weight but stay healthy
We, the physicians should not advise patients to become overweight from normal BMI on the basis of “obesity paradox”. Overweight individuals, if the high weight due to visceral fat will obviously lead to metabolic abnormalities, higher insulin resistance and subsequent cardiovascular adverse outcomes. I think if higher weight is due to lean mass or subcutaneous fat or in special cases due to high brown fat content, these persons are physically more fit than normal weight persons. I think we should differentiate healthy overweight from unhealthy lean. We should advise patients not to gain weight but stay healthy.
The Obesity Paradox in Type 2 Diabetes Mellitus. Ann Intern Med. 2015;162:I–26. doi: https://doi.org/10.7326/P15-9015
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Published: Ann Intern Med. 2015;162(9):I-26.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism, Obesity.
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