DAVID A. LIPSCHITZ, M.D., Ph.D.; SAMUEL GOLDSTEIN, M.D.; ROBERT REIS, Ph.D.; MARC E. WEKSLER, M.D.; RUBIN BRESSLER, M.D.; BARBARA A. NEILAN, M.D.
The incidence of cancer increases progressively with age. Rearrangements of genomes have been found to accompany cellular aging. These factors, in concert with age-dependent alterations in immune function and host defense, may help to explain the increased risk of malignant disease in aged persons. The clinical presentation and natural history of neoplasia are also affected by aging. This conference reviews recent developments in these areas, examines the effects of drug use in the elderly and implications for management, and discusses current information on how age may influence the response of cancer to therapy.
The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.
LIPSCHITZ DA, GOLDSTEIN S, REIS R, et al. Cancer in the Elderly: Basic Science and Clinical Aspects. Ann Intern Med. 1985;102:218–228. doi: https://doi.org/10.7326/0003-4819-102-2-218
Download citation file:
Published: Ann Intern Med. 1985;102(2):218-228.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use