A. Cecile J.W. Janssens, PhD; John P.A. Ioannidis, MD, DSc; Cornelia M. van Duijn, PhD; Julian Little, PhD; Muin J. Khoury, MD, PhD; for the GRIPS Group
The rapid and continuing progress in gene discovery for complex diseases is fueling interest in the potential application of genetic risk models for clinical and public health practice.
The number of studies assessing the predictive ability is steadily increasing, but the quality and completeness of reporting varies.
A multidisciplinary workshop sponsored by the Human Genome Epidemiology Network developed a checklist of 25 items recommended for strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS), building on the principles established by prior reporting guidelines.
These recommendations aim to enhance the transparency of study reporting, and thereby to improve the synthesis and application of information from multiple studies that might differ in design, conduct, or analysis.
A detailed Explanation and Elaboration document is published at www.plosmedicine.org.
The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.
Janssens ACJ, Ioannidis JP, van Duijn CM, Little J, Khoury MJ, for the GRIPS Group. Strengthening the Reporting of Genetic Risk Prediction Studies: The GRIPS Statement. Ann Intern Med. 2011;154:421–425. doi: 10.7326/0003-4819-154-6-201103150-00008
Download citation file:
Published: Ann Intern Med. 2011;154(6):421-425.
Research and Reporting Methods.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use