Gregory M. Lucas, MD; Richard E. Chaisson, MD; Richard D. Moore, MD, MHSc
Unselected patients in whom highly active antiretroviral therapy is started in a clinic setting achieve viral suppression substantially less frequently than do patients in controlled clinical trials. Missed clinic visits were the most important risk factor for failure to suppress HIV-1 RNA levels.
Ann Intern Med. 1999;131(2):81-87. doi:10.7326/0003-4819-131-2-199907200-00002
Gideon Steinbach, MD, PhD; Richard Ford, MD, PhD; Gary Glober, MD; Dory Sample, RN; Frederick B. Hagemeister, MD; Patrick M. Lynch, MD, JD; Peter W. McLaughlin, MD; Maria A. Rodriguez, MD; Jorge E. Romaguera, MD; Andreas H. Sarris, MD, PhD; Anas Younes, MD; Rajyalakshmi Luthra, PhD; John T. Manning, MD; Constance M. Johnson, BSN; Sandeep Lahoti, MD; Yu Shen, PhD; Jeffrey E. Lee, MD; Rodger J. Winn, MD; Robert M. Genta, MD; David Y. Graham, MD; Fernando F. Cabanillas, MD
A subset of Helicobacter pylori–positive gastric mucosa-associated lymphoid tissue lymphomas, including infiltrative tumors, may respond to antibiotic treatment. The likelihood of early complete remission seems to be greatest for superficial and distal tumors.
Ann Intern Med. 1999;131(2):88-95. doi:10.7326/0003-4819-131-2-199907200-00003
E. Wesley Ely, MD, MPH; Gregory W. Evans, MA; Edward F. Haponik, MD
It has been argued that life support for the elderly should be limited to conserve resources. In this study, after adjustment for severity of illness, elderly patients spent similar lengths of time on mechanical ventilation and in the intensive care unit and hospital but had a lower cost of care than younger patients. These differences are not explained by differences in mortality rates.
Ann Intern Med. 1999;131(2):96-104. doi:10.7326/0003-4819-131-2-199907200-00004
Ranjan P. Ghose, MD; Phillip M. Hall, MD; Emmanuel L. Bravo, MD
Medical management of aldosterone-producing adenomas is a viable option for controlling blood pressure and serum potassium levels.
Ann Intern Med. 1999;131(2):105-108. doi:10.7326/0003-4819-131-2-199907200-00005
Terri R. Fried, MD; Carol van Doorn, PhD; John R. O'Leary, MA; Mary E. Tinetti, MD; Margaret A. Drickamer, MD
Preference for home as the site of care for terminal illness exceeds existing practice. However, the current debate about home versus hospital as the ideal site for end-of-life care may ignore an issue important to older persons—namely, the care of disabilities that precede death.
Ann Intern Med. 1999;131(2):109-112. doi:10.7326/0003-4819-131-2-199907200-00006
Jacques G.H. Gubler, MD; Marcel Kuster, MD; Fabrizio Dutly, PhD; Fridolin Bannwart, MD; Martin Krause, MD; Hans Peter Vögelin, MD; Gianni Garzoli, MD; Martin Altwegg, PhD
Cardiac manifestations of Whipple disease are rarely diagnosed before autopsy. In four patients with culture-negative endocarditis, the absence of clinical, microscopic, or microbiological evidence of gastrointestinal disease did not rule out Tropheryma whippelii.
Ann Intern Med. 1999;131(2):112-116. doi:10.7326/0003-4819-131-2-199907200-00007
Elizabeth J. Suh-Burgmann, MD; Annekathryn Goodman, MD
This paper reviews the literature on the occurrence of endometrial cancer in women taking tamoxifen and the usefulness of various screening methods in this setting. Risk factors and screening criteria for endometrial cancer in the general population are discussed, and a strategy for surveillance of women taking tamoxifen is proposed.
Ann Intern Med. 1999;131(2):127-135. doi:10.7326/0003-4819-131-2-199907200-00009
Steven H. Brown, MS, MD; Randolph A. Miller, MD; Henry N. Camp, BA; Dario A. Guise, DrIng; H. Kenneth Walker, MD
The authors describe a novel, empirical approach to deriving an electronic, clinically useful, canonical problem list vocabulary. The resulting Canonical Clinical Problem Statement System was compared with existing vocabularies used by the National Library of Medicine.
Ann Intern Med. 1999;131(2):117-126. doi:10.7326/0003-4819-131-2-199907200-00008
Frederick M. Hecht, MD; Ira B. Wilson, MD, MSc; Albert W. Wu, MD; Robert L. Cook, MD, MPH; Barbara J. Turner, MD; for the Society of General Internal Medicine AIDS Task Force
Treatment advances and outcomes data have raised new concerns about how to optimize care for patients with HIV infection. What is the role of experience and expertise in optimizing outcomes for these patients? What is the role of primary care skills in high-quality HIV care? How good is primary care physicians' basic HIV knowledge in screening and prevention?
Ann Intern Med. 1999;131(2):136-143. doi:10.7326/0003-4819-131-2-199907200-00011
Didier Raoult, MD, PhD
In this issue, Gubler and colleagues report that chronic afebrile endocarditis could be caused by Whipple disease bacterium in patients whose clinical picture does not suggest classic infective endocarditis. Our knowledge of Whipple disease is growing rapidly, but culture of the bacterium is necessary to develop a serologic test and to determine whether the bacterium is a unique pathotype.
Ann Intern Med. 1999;131(2):144-146. doi:10.7326/0003-4819-131-2-199907200-00012
Anthony E. Voytovich, MD
Brown and colleagues, in this issue, describe their elegant and ambitious efforts to distill a workable canonical vocabulary from the large number of raw problem statements used in one institution. What are the benefits of a more critical use of words and diagnostic concepts?
Ann Intern Med. 1999;131(2):146-147. doi:10.7326/0003-4819-131-2-199907200-00013
Tim Wolter, MD
The three Fates stood in judgment of human fortunes, from which there could be no appeal. Despite our ever-increasing medical knowledge, the Fates still seem to be at work.
Ann Intern Med. 1999;131(2):148-149. doi:10.7326/0003-4819-131-2-199907200-00014
Pain is the leitmotif of my life, but despite all the restrictions I'm still able to lead a self-reliant, happy existence.
Ann Intern Med. 1999;131(2):150-152. doi:10.7326/0003-4819-131-2-199907200-00015
Ann Intern Med. 1999;131(2):154. doi:10.7326/0003-4819-131-2-199907200-00016
Ann Intern Med. 1999;131(2):154. doi:10.7326/0003-4819-131-2-199907200-00017
Ann Intern Med. 1999;131(2):154-155. doi:10.7326/0003-4819-131-2-199907200-00018
Ann Intern Med. 1999;131(2):155. doi:10.7326/0003-4819-131-2-199907200-00019
Ann Intern Med. 1999;131(2):155. doi:10.7326/0003-4819-131-2-199907200-00020
Ann Intern Med. 1999;131(2):155-156. doi:10.7326/0003-4819-131-2-199907200-00021
Ann Intern Med. 1999;131(2):156-157. doi:10.7326/0003-4819-131-2-199907200-00022
Ann Intern Med. 1999;131(2):157. doi:10.7326/0003-4819-131-2-199907200-00023
Ann Intern Med. 1999;131(2):157-158. doi:10.7326/0003-4819-131-2-199907200-00024
Ann Intern Med. 1999;131(2):158. doi:10.7326/0003-4819-131-2-199907200-00025
Ann Intern Med. 1999;131(2):158. doi:10.7326/0003-4819-131-2-199907200-00026
Ann Intern Med. 1999;131(2):161-164. doi:10.7326/0003-4819-131-2-199907200-00101
Kathleen Franco-Bronson, MD
Ann Intern Med. 1999;131(2):135. doi:10.7326/0003-4819-131-2-199907200-00010
Aradhana Venkatesan, BA; Mark Aronson, MD
Ann Intern Med. 1999;131(2):159. doi:10.7326/0003-4819-131-2-199907200-00027
Albert B. Knapp, MD
Ann Intern Med. 1999;131(2):159-160. doi:10.7326/0003-4819-131-2-199907200-00028
Michael D. Fetters, MD, MPH, MA
Ann Intern Med. 1999;131(2):160. doi:10.7326/0003-4819-131-2-199907200-00029
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