Maria Celia B. Hughes, MMedSci; Gail M. Williams, PhD; Peter Baker, PhD; Adèle C. Green, MBBS, PhD
Whether sunscreen or dietary supplements, such as β-carotene, protect against skin aging has not been established. In this randomized trial, participants assigned to daily application of sunscreen showed less skin aging after 4 years than those assigned to discretionary use. No difference in skin aging was shown with daily β-carotene supplementation compared with placebo, but these findings need confirmation before firm conclusions can be made.
Ann Intern Med. 2013;158(11):781-790. doi:10.7326/0003-4819-158-11-201306040-00002
Catherine M. DesRoches, DrPH; Anne-Marie Audet, MD; Michael Painter, MD; Karen Donelan, ScD
The Centers for Medicare & Medicaid Services provides incentive payments to physicians who meet electronic health record (EHR) meaningful use criteria. Whether most physicians with EHRs are able to meet these criteria is unknown. Approximately 40% of physicians in this national survey reported using an EHR, but only 1 in 10 reported being able to use it to meet meaningful use criteria and half believed that it was difficult to meet at least some criteria. The authors conclude that EHR adoption does not necessarily ensure better patient management.
Ann Intern Med. 2013;158(11):791-799. doi:10.7326/0003-4819-158-11-201306040-00003
David R. Anderson, MD; Michael J. Dunbar, MD; Eric R. Bohm, MD; Etienne Belzile, MD; Susan R. Kahn, MD; David Zukor, MD; William Fisher, MD; Wade Gofton, MD; Peter Gross, MD; Stephane Pelet, MD; Mark Crowther, MD; Steven MacDonald, MD; Paul Kim, MD; Susan Pleasance, BScN; Nicki Davis, BSc; Pantelis Andreou, PhD; Philip Wells, MD; Michael Kovacs, MD; Marc A. Rodger, MD; Tim Ramsay, PhD; Marc Carrier, MD; Pascal-Andre Vendittoli, MD
The role of aspirin in thromboprophylaxis after total hip arthroplasty (THA) is controversial. This trial randomly assigned THA patients to 28 days of aspirin or dalteparin after an initial 10 days of dalteparin and found that aspirin was noninferior for preventing venous thromboembolism and caused less bleeding. However, the trial was stopped early because of slow enrollment, so findings are based on very few events. These findings suggest that aspirin may be a reasonable alternative to low-molecular-weight heparin for extended thromboprophylaxis among THA patients after 10 days of low-molecular-weight heparin.
Ann Intern Med. 2013;158(11):800-806. doi:10.7326/0003-4819-158-11-201306040-00004
Roger Chou, MD; Ngoc Wasson, MPH
This review examined evidence on the accuracy of blood tests to diagnose fibrosis in patients with chronic hepatitis C virus (HCV) infection. Evidence shows that platelet count, the age–platelet index, the aspartate aminotransferase–platelet ratio index (APRI), FibroIndex, FibroTest, and the Forns index are moderately useful for identifying fibrosis. Platelet count, the age–platelet index, APRI, and Hepascore were moderately useful for identifying cirrhosis. The findings suggest that blood tests can help to identify HCV-infected patients with clinically significant fibrosis, with somewhat greater accuracy for identifying cirrhosis than for less advanced fibrosis.
Ann Intern Med. 2013;158(11):807-820. doi:10.7326/0003-4819-158-11-201306040-00005
Ruth Etzioni, PhD; Roman Gulati, MS; Leslie Mallinger, MPH; Jeanne Mandelblatt, MD, MPH
Estimates of the frequency of overdiagnosis in breast and prostate cancer screening vary greatly across studies. Investigators examined features of published studies that influence estimates of overdiagnosis, including overdiagnosis definition and measurement, contextual features, and estimation approach. Understanding how these features affect results will help policymakers, clinicians, and patients interpret estimates of cancer overdiagnosis.
Ann Intern Med. 2013;158(11):831-838. doi:10.7326/0003-4819-158-11-201306040-00008
Janet A. Schlechte, MD
This Update summarizes studies published in 2012 that the authors consider highly relevant to the practice of endocrinology. Topics include diabetes mellitus, thyroid disease, and osteoporosis.
Ann Intern Med. 2013;158(11):821-824. doi:10.7326/0003-4819-158-11-201306040-00106
Paul E. Stevens, MBBS, BSc; Adeera Levin, MD, BSc; for the Kidney Disease: Improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group Members*
The Kidney Disease: Improving Global Outcomes (KDIGO) organization developed clinical practice guidelines in 2012 to provide guidance on the evaluation, management, and treatment of chronic kidney disease (CKD) in adults and children who are not receiving renal replacement therapy. This synopsis focuses on key recommendations from the guideline pertinent to identification, classification, monitoring, and management of CKD in adults.
Ann Intern Med. 2013;158(11):825-830. doi:10.7326/0003-4819-158-11-201306040-00007
Daniel Grossman, MD
In December 2012, the American College of Obstetricians and Gynecologists released a Committee Opinion supporting over-the-counter access to oral contraceptive pills. This commentary makes a case that over-the-counter provision of oral contraceptive pills is both safe and effective for reducing unintended pregnancies.
Ann Intern Med. 2013;158(11):839-840. doi:10.7326/0003-4819-158-11-201306040-00629
Hillary V. Kunins, MD, MPH, MS; Thomas A. Farley, MD, MPH; Deborah Dowell, MD, MPH
In January 2013, the New York City Department of Health and Mental Hygiene released guidelines to help reduce the misuse of prescription opioid analgesics by establishing standards for prescribing from the emergency department. In this commentary, authors employed by the department discuss the recommendations and why they are likely to help emergency and other physicians provide safer care for patients with pain.
Ann Intern Med. 2013;158(11):841-842. doi:10.7326/0003-4819-158-11-201306040-00631
Alex M. Rosenau, DO
In January 2013, the New York City Department of Health and Mental Hygiene released guidelines to help reduce the misuse of prescription opioid analgesics by establishing standards for prescribing from the emergency department. In this commentary, the President-Elect of the American College of Emergency Physicians argues that restricting opioid prescription by emergency physicians will not solve the problem of opioid misuse. Rather, closing corrupt pain centers and improving access to high-quality nonemergency care will improve the care of patients with pain.
Ann Intern Med. 2013;158(11):843-844. doi:10.7326/0003-4819-158-11-201306040-00632
Ross Koppel, PhD
In this issue, DesRoches and colleagues examined physician use of EHR systems to manage their patient populations and their expectations of the influence of EHRs on health care outcomes and costs. The editorialist discusses the study and its findings and concludes that our focus must shift from EHR use to EHR utility.
Ann Intern Med. 2013;158(11):845-846. doi:10.7326/0003-4819-158-11-201306040-00012
A. M. Horowitz, MFA
The road to becoming a physician is a grueling one. But in the end, doctors experience the reward of knowing they have healed someone or eased their pain. The family members of physicians share in many of the sacrifices the medical profession exacts on its doctors but never experience the satisfaction.
Ann Intern Med. 2013;158(11):847. doi:10.7326/0003-4819-158-11-201306040-00013
Ann Intern Med. 2013;158(11):849. doi:10.7326/0003-4819-158-11-201306040-00015
Ann Intern Med. 2013;158(11):849. doi:10.7326/0003-4819-158-11-201306040-00016
Ann Intern Med. 2013;158(11):849-850. doi:10.7326/0003-4819-158-11-201306040-00017
Ann Intern Med. 2013;158(11):850. doi:10.7326/0003-4819-158-11-201306040-00018
Ann Intern Med. 2013;158(11):850-851. doi:10.7326/0003-4819-158-11-201306040-00019
Ann Intern Med. 2013;158(11):851. doi:10.7326/0003-4819-158-11-201306040-00020
Ann Intern Med. 2013;158(11):851-852. doi:10.7326/0003-4819-158-11-201306040-00021
Ann Intern Med. 2013;158(11):852. doi:10.7326/0003-4819-158-11-201306040-00022
Ann Intern Med. 2013;158(11):852. doi:10.7326/0003-4819-158-11-201306040-00023
Jason D. Eubanks, MD
Ann Intern Med. 2013;158(11):848. doi:10.7326/0003-4819-158-11-201306040-00014
Linda A. Jacobs, PhD, RN; David J. Vaughn, MD
Ann Intern Med. 2013;158(11):ITC6-1. doi:10.7326/0003-4819-158-11-201306040-01006
Ann Intern Med. 2013;158(11):I-28. doi:10.7326/0003-4819-158-11-201306040-00001
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