Raine Sihvonen, MD, PhD; Martin Englund, MD, PhD; Aleksandra Turkiewicz, MSc; Teppo L.N. Järvinen, MD, PhD; for the Finnish Degenerative Meniscal Lesion Study Group
Whether arthroscopic partial meniscectomy is effective for mechanical symptoms of the knee associated with degenerative meniscal tears is unclear. This secondary analysis of data from a randomized, controlled trial compared the effect of arthroscopic partial meniscectomy with sham surgery on relief of mechanical symptoms among patients with degenerative meniscal tears.
Ann Intern Med. 2016;164(7):449-455. doi:10.7326/M15-0899
Christopher D. Jensen, PhD, MPH; Douglas A. Corley, MD, PhD; Virginia P. Quinn, PhD, MPH; Chyke A. Doubeni, MD, MPH; Ann G. Zauber, PhD; Jeffrey K. Lee, MD, MAS; Wei K. Zhao, MPH; Amy R. Marks, MPH; Joanne E. Schottinger, MD; Nirupa R. Ghai, PhD; Alexander T. Lee, MD; Richard Contreras, MS; Carrie N. Klabunde, PhD; Charles P. Quesenberry, PhD; Theodore R. Levin, MD; Pauline A. Mysliwiec, MD
New immunochemical cancer screening tests can decrease deaths from colorectal cancer by detecting small amounts of occult blood in stool. Whether test sensitivity and accuracy decreases through repeated use over several years is unknown. This study measured acceptance and performance characteristics of these tests during the first 4 years of a large screening program.
Ann Intern Med. 2016;164(7):456-463. doi:10.7326/M15-0983
Timothy Hudson Rainer, MD; Chi Hung Cheng, MD; Hein J.E.M. Janssens, MD, PhD; Chi Yin Man, MD; Lai Shan Tam, MD; Yu Fai Choi, MD; Wah Hon Yau, MD; Ka Hing Lee, MD; Colin Alexander Graham, MD
Two recent randomized, controlled trials showed that oral corticosteroids and nonsteroidal anti-inflammatory drugs were similarly effective in treating acute gout symptoms, but the trials had small samples and other methodological limitations. This large pragmatic trial compared the analgesic effectiveness and safety of oral prednisolone versus indomethacin in the treatment of acute gout.
Ann Intern Med. 2016;164(7):464-471. doi:10.7326/M14-2070
David Collister, MD; Paul Komenda, MD, MHA, CHE; Brett Hiebert, MSc; Ravindi Gunasekara, BSc; Yang Xu, MD, BSc (Pharm); Frederick Eng, BSc; Blake Lerner, BSc; Kerry Macdonald, MLIS; Claudio Rigatto, MD, MSc; Navdeep Tangri, MD, PhD
This meta-analysis of 17 studies examines whether erythropoietin-stimulating agents improve health-related quality of life in patients with anemia of chronic kidney disease.
Ann Intern Med. 2016;164(7):472-478. doi:10.7326/M15-1839
Gerald W. Smetana, MD; Donald E. Cutlip, MD; Duane S. Pinto, MD, MPH
This Grand Rounds discussion summarizes a conversation between 2 cardiologists about screening for coronary heart disease in asymptomatic patients with varying degrees of risk. The discussants provide recommendations for a specific patient who is uncertain whether to proceed with screening.
Ann Intern Med. 2016;164(7):479-487. doi:10.7326/M15-2910
Matthew Nielsen, MD, MS; Amir Qaseem, MD, PhD; for the High Value Care Task Force of the American College of Physicians
Hematuria is frequently encountered in clinical practice and presents as grossly visible blood in the urine or microscopic hematuria noted on urinalysis. This article from the American College of Physicians provides advice for practicing clinicians about the indications for evaluating hematuria as a potential marker of occult urinary tract cancer.
Ann Intern Med. 2016;164(7):488-497. doi:10.7326/M15-1496
David U. Himmelstein, MD; Russell S. Phillips, MD
Should asymptomatic patients schedule annual visits with their physicians? Many experts and some professional organizations say no and cite evidence-based studies as the reason why. This article examines those studies and reaches more nuanced conclusions.
Ann Intern Med. 2016;164(7):498-499. doi:10.7326/M15-2097
Aaron S. Kesselheim, MD, JD, MPH; Thomas J. Hwang, AB
In 2012, Congress gave the U.S. Food and Drug Administration (FDA) authority to designate new drugs with promise of substantial benefit as “breakthrough” drugs and then take steps to expedite their pathway to possible approval. Congress is now deciding whether to grant the FDA the authority to give medical devices the same designation. This article examines the risks, benefits, and ethical considerations of that decision.
Ann Intern Med. 2016;164(7):500-502. doi:10.7326/M15-1906
Jeffrey N. Katz, MD, MSc; Morgan H. Jones, MD, MPH
In this issue, Sihvonen and colleagues' randomized, controlled trial demonstrated that arthroscopic partial meniscectomy is no more beneficial than arthroscopic lavage without meniscal resection to reduce catching and locking in patients with degenerative meniscal tear. The editorialists discuss how these findings illustrate that diagnostic and therapeutic paradigms derived from the management of younger persons without coexisting problems may not translate to older persons with more complex pathoanatomy.
Ann Intern Med. 2016;164(7):503-504. doi:10.7326/M16-0049
Darren B. Taichman, MD, PhD; Joyce Backus, MSLS; Christopher Baethge, MD; Howard Bauchner, MD; Peter W. de Leeuw, MD; Jeffrey M. Drazen, MD; John Fletcher, MB, BChir, MPH; Frank A. Frizelle, MBChB, FRACS; Trish Groves, MBBS, MRCPsych; Abraham Haileamlak, MD; Astrid James, MBBS; Christine Laine, MD, MPH; Larry Peiperl, MD; Anja Pinborg, MD; Peush Sahni, MBBS, MS, PhD; Sinan Wu, MD
The International Committee of Medical Journal Editors (ICMJE) believes that there is an ethical obligation to responsibly share data generated by interventional clinical trials because participants have put themselves at risk. In this commentary, ICMJE editors outline proposed requirements to help meet this obligation.
Ann Intern Med. 2016;164(7):505-506. doi:10.7326/M15-2928
Bernard L. Sussman, MD
Mr. W had been born in a German town near Leipzig. I was interested in the prewar years and asked about his youth. I also asked about the war years. He was slow to respond, perhaps considering whether to proceed, but I encouraged him to tell his story.
Ann Intern Med. 2016;164(7):507-508. doi:10.7326/M15-1759
Ann Intern Med. 2016;164(7):509-510. doi:10.7326/L15-0522
Ann Intern Med. 2016;164(7):509. doi:10.7326/L15-0523
Ann Intern Med. 2016;164(7):510-511. doi:10.7326/L15-0568
Ann Intern Med. 2016;164(7):510. doi:10.7326/L15-0569
Ann Intern Med. 2016;164(7):511-512. doi:10.7326/L16-0097
Ann Intern Med. 2016;164(7):511. doi:10.7326/L16-0098
D.A. Frater, MD
Ann Intern Med. 2016;164(7):487. doi:10.7326/M15-3067
Stanley Cohen, MD
Ann Intern Med. 2016;164(7):502. doi:10.7326/M15-2107
Christine A. Pace, MD, MSc; Jeffrey H. Samet, MD, MA, MPH
Ann Intern Med. 2016;164(7):ITC49-ITC64. doi:10.7326/AITC201604050
Darren B. Taichman, MD, PhD
Ann Intern Med. 2016;164(7):ED7. doi:10.7326/AFED201604050
Nathan Gray, MD
Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.
Ann Intern Med. 2016;164(7):W12. doi:10.7326/G15-0020
Ann Intern Med. 2016;164(7):I-34. doi:10.7326/P16-9007
Ann Intern Med. 2016;164(7):I-15. doi:10.7326/P16-9008
Ann Intern Med. 2016;164(7):I-30. doi:10.7326/P16-9011
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