John P. Greenwood, MB ChB, PhD; Bernhard A. Herzog, MD; Julia M. Brown, MSc; Colin C. Everett, MSc; Jane Nixon, PhD; Petra Bijsterveld, MA; Neil Maredia, MB ChB, MD; Manish Motwani, MB ChB, PhD; Catherine J. Dickinson, BM BCh, MA, PhD; Stephen G. Ball, MB BChir, PhD; Sven Plein, MD, PhD
Several tests are useful for deciding whether coronary artery disease is present and how severe it is. Clinicians frequently use images of the heart taken during rest and again during stress that are produced by single-photon emission computed tomography or magnetic resonance. This study examines patients who had both tests and determines which test more accurately predicted major adverse cardiovascular events during the following 6 to 7 years.
Ann Intern Med. 2016;165(1):1-9. doi:10.7326/M15-1801
Cora L. Bernard, MS; Margaret L. Brandeau, PhD; Keith Humphreys, PhD; Eran Bendavid, MD, MS; Mark Holodniy, MD; Christopher Weyant, MS; Douglas K. Owens, MD, MS; Jeremy D. Goldhaber-Fiebert, PhD
The total population health benefits and costs of HIV preexposure prophylaxis (PrEP) for people who inject drugs (PWID) in the United States are unclear. This study found that PrEP, with frequent screening and prompt treatment for HIV, can reduce HIV burden among PWID and provide health benefits for the entire U.S. population. However, it remains an expensive intervention.
Ann Intern Med. 2016;165(1):10-19. doi:10.7326/M15-2634
Isuru Ranasinghe, MBChB, MMed, PhD; Craig S. Parzynski, MS; James V. Freeman, MD, MPH; Rachel P. Dreyer, PhD; Joseph S. Ross, MD, MHS; Joseph G. Akar, MD, PhD; Harlan M. Krumholz, MD, MS; Jeptha P. Curtis, MD
Although the short-term risks for complications after placement of implantable cardioverter-defibrillators (ICDs) are well-established, little is known about longer-term risks. This large national study evaluated long-term complications after ICD placement as well as the patient and device factors associated with them.
Ann Intern Med. 2016;165(1):20-29. doi:10.7326/M15-2732
Nancy Greer, PhD; Jennifer Bolduc, PharmD; Eric Geurkink, PharmD; Thomas Rector, PhD, PharmD; Kimberly Olson, MD; Eva Koeller, BA; Roderick MacDonald, MS; Timothy J. Wilt, MD, MPH
This comprehensive review involving 65 patient populations examined the benefits and harms of pharmacist-led chronic disease management for community-dwelling adults. It found that pharmacist-led chronic disease management was associated with effects similar to those of usual care for resource utilization and may improve physiologic goal attainment.
Ann Intern Med. 2016;165(1):30-40. doi:10.7326/M15-3058
Kristin J. Cummings, MD, MPH; Mary J. Choi, MD, MPH; Eric J. Esswein, MSPH, CIH; Marie A. de Perio, MD; Joshua M. Harney, MS, CIH; Wendy M. Chung, MD, MS; David L. Lakey, MD; Allison M. Liddell, MD; Pierre E. Rollin, MD
Health care personnel caring for patients with Ebola virus disease (EVD) are at increased risk for infection. This article describes infection control measures implemented at a community hospital to strengthen the hospital's capacity to safely diagnose and treat patients with EVD.
Ann Intern Med. 2016;165(1):41-49. doi:10.7326/M15-2944
Hilary Daniel, BS; for the Health and Public Policy Committee of the American College of Physicians
The United States pays more for some prescription drugs than other developed countries, and the price and increasing costs associated with prescription medication is a major concern for patients, physicians, and payers. This paper reports policy recommendations from the American College of Physicians to address the escalating costs of prescription drugs in the United States.
Ann Intern Med. 2016;165(1):50-52. doi:10.7326/M15-2768
Shmuel Shoham, MD; Annukka A.R. Antar, MD, PhD; Paul G. Auwaerter, MD, MBA; Christine M. Durand, MD; Mark S. Sulkowski, MD; Deborah J. Cotton, MD, MPH
When shortages of antimicrobials are coupled with the dynamics of serious infections, the results can be catastrophic. The authors discuss possible incentives, programs, and regulations that could help to combat the problem.
Ann Intern Med. 2016;165(1):53-54. doi:10.7326/M15-3076
Roy M. Poses, MD; Wally R. Smith, MD
This commentary discusses how clauses in the contracts that physicians sign with their employers or that their employers sign with third parties may be part of a growing class of subtle restrictions on employed physicians' professionalism and autonomy.
Ann Intern Med. 2016;165(1):55-56. doi:10.7326/M15-2979
Evan M. Bloch, MD, MS; Matthew S. Simon, MD, MS; Beth H. Shaz, MD
This commentary argues that new economic challenges and the emergence of global pathogens, such as Zika virus, call for new investments in blood bank infrastructure and testing technologies, as well as improved collaboration among stakeholders.
Ann Intern Med. 2016;165(1):57-58. doi:10.7326/M15-1329
Hal C. Lawrence, MD
In this commentary, the Chief Executive Officer of the American Congress of Obstetricians and Gynecologists describes how pharmacist prescription of oral contraceptives exchanges one barrier for another and why over-the-counter availability would be a better strategy for increasing access to safe, effective birth control.
Ann Intern Med. 2016;165(1):59-60. doi:10.7326/M15-3003
M.G. Myriam Hunink, MD, PhD; Kirsten E. Fleischmann, MD, MPH
Greenwood and colleagues report the prognostic performance of stress cardiovascular magnetic resonance and single-photon emission computed tomography in patients with suspected coronary heart disease. The editorialists discuss the challenges of evaluation and how both randomized and nonrandomized studies contribute important information about diagnostic strategies.
Ann Intern Med. 2016;165(1):61-62. doi:10.7326/M16-0811
Rochelle P. Walensky, MD, MPH
Bernard and colleagues' study highlights key points about PrEP for PWID, one of which is the staggering financial resources required. However, deaths due to opioid overdose in 2014 eclipsed the number of deaths at the peak of the HIV epidemic in the United States. As a result, now is the time to be maximally efficient with HIV prevention resources to ensure their greatest impact.
Ann Intern Med. 2016;165(1):63-64. doi:10.7326/M16-0788
Jamie K. Lim, BSc
Ann Intern Med. 2016;165(1):65-66. doi:10.7326/M15-2247
William T. Pordy, MD
Ann Intern Med. 2016;165(1):66. doi:10.7326/M15-2351
Ann Intern Med. 2016;165(1):67. doi:10.7326/L16-5012
Ann Intern Med. 2016;165(1):67-68. doi:10.7326/L16-5013
Ann Intern Med. 2016;165(1):68. doi:10.7326/L16-5014
Ann Intern Med. 2016;165(1):68-69. doi:10.7326/L15-0627
Ann Intern Med. 2016;165(1):69. doi:10.7326/L15-0626
Ann Intern Med. 2016;165(1):69-70. doi:10.7326/L15-0628
Ann Intern Med. 2016;165(1):70-71. doi:10.7326/L16-0010
Ann Intern Med. 2016;165(1):71. doi:10.7326/L16-5011
Ann Intern Med. 2016;165(1):71-72. doi:10.7326/L16-0008
Ann Intern Med. 2016;165(1):72. doi:10.7326/L16-5009
Ann Intern Med. 2016;165(1):73-74. doi:10.7326/L16-0069
Ann Intern Med. 2016;165(1):73. doi:10.7326/L16-0070
Ann Intern Med. 2016;165(1):74-75. doi:10.7326/L16-0071
Ann Intern Med. 2016;165(1):74. doi:10.7326/L16-0072
Ann Intern Med. 2016;165(1):75-76. doi:10.7326/L15-0532
Tuhina Neogi, MD, PhD
Ann Intern Med. 2016;165(1):ITC1-ITC16. doi:10.7326/AITC201607050
Darren B. Taichman, MD, PhD
Ann Intern Med. 2016;165(1):ED1. doi:10.7326/AFED201607050
Grace E. Farris, MD
Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.
Ann Intern Med. 2016;165(1):W1-W4. doi:10.7326/G16-0003
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