Issues

Hans Wouters, PhD; Jessica Scheper, MD; Hedi Koning, MSc; Chris Brouwer, MSc; Jos W. Twisk, PhD; Helene van der Meer, MSc; Froukje Boersma, MD, PhD; Sytse U. Zuidema, MD, PhD; Katja Taxis, PhD

Inappropriate prescribing of medications is a common problem that is associated with increased risk for adverse outcomes in older adults. The effectiveness of medication management in improving prescribing in nursing home residents is uncertain. This randomized controlled trial examined the effect of a multidisciplinary medication review performed by physicians and pharmacists on the discontinuation of inappropriate medication use and clinical outcomes among nursing home residents.

Ann Intern Med. 2017;167(9):609-617. doi:10.7326/M16-2729

Rochelle P. Walensky, MD, MPH; Ethan D. Borre, BA; Linda-Gail Bekker, MD, PhD; Emily P. Hyle, MD, MSc; Gregg S. Gonsalves, PhD; Robin Wood, MMed, DSc (Med); Serge P. Eholié, MD, MSc; Milton C. Weinstein, PhD; Xavier Anglaret, MD, PhD; Kenneth A. Freedberg, MD, MSc; A. David Paltiel, PhD, MBA

Anticipating significant cuts in global foreign aid, researchers estimate the likely clinical, epidemiologic, and economic impact of reduced investment in HIV prevention and care. The study considers both the long-term savings likely to accrue to donor nations and how recipient nations might tailor their response to minimize adverse health effects.

Ann Intern Med. 2017;167(9):618-629. doi:10.7326/M17-1358

Jenifer M. Brown, MD; Cassianne Robinson-Cohen, PhD; Miguel Angel Luque-Fernandez, MSc, MPH, PhD; Matthew A. Allison, MD, MPH; Rene Baudrand, MD; Joachim H. Ix, MD, MS; Bryan Kestenbaum, MD, MS; Ian H. de Boer, MD, MS; Anand Vaidya, MD, MMSc

Primary aldosteronism is the most common and modifiable form of secondary hypertension and is usually considered when the classic phenotype of severe hypertension or hypokalemia is encountered. This study assessed whether a spectrum of subclinical primary aldosteronism that increases risk for hypertension exists among normotensive persons.

Ann Intern Med. 2017;167(9):630-641. doi:10.7326/M17-0882

Xin-Lin Zhang, MD; Qing-Qing Zhu, MD; Li-Na Kang, MD; Xue-Ling Li, MD; Biao Xu, MD, PhD

Percutaneous coronary interventions to implant bioresorbable vascular scaffolds (BVSs) were designed to reduce the late thrombotic events that occur with metallic stents. This meta-analysis of 7 trials and 38 observational studies provides important data regarding the incidence of thrombosis after BVS implantation and compares everolimus-eluting BVSs with everolimus-eluting metallic stents in terms of mid- and long-term safety and efficacy.

Ann Intern Med. 2017;167(9):642-654. doi:10.7326/M17-1101

Paul R. Conlin, MD; Jeffrey Colburn, MD; David Aron, MD, MS; Rose Mary Pries, DrPH; Mark P. Tschanz, DO; Leonard Pogach, MD, MBA

This synopsis summarizes key features of the 2017 joint clinical practice guideline from the U.S. Department of Veterans Affairs and the U.S. Department of Defense for the management of type 2 diabetes mellitus.

Ann Intern Med. 2017;167(9):655-663. doi:10.7326/M17-1362

Daniel R. Lucey, MD, MPH; Halsie Donaldson, MS

Although a safe and effective vaccine is available for yellow fever, it is in very short supply. The author discusses the global implications of this shortage and outlines scientific and programmatic initiatives needed to ensure a future robust vaccine supply.

Ann Intern Med. 2017;167(9):664-665. doi:10.7326/M17-1337

Carol J. Hogue, PhD, MPH; Kelli Stidham Hall, PhD, MS; Melissa Kottke, MD, MPH, MBA

Several prominent voices in federal leadership positions have recently disseminated misinformation on contraception that runs counter to widely accepted, evidence-based research and may cause harm by discouraging beneficial contraceptive use.

Ann Intern Med. 2017;167(9):666-667. doi:10.7326/M17-2011

Gregory E. Simon, MD, MPH; Gloria Coronado, PhD; Lynn L. DeBar, PhD, MPH; Laura M. Dember, MD; Beverly B. Green, MD, MPH; Susan S. Huang, MD, MPH; Jeffrey G. Jarvik, MD, MPH; Vincent Mor, PhD; Joakim Ramsberg, PhD; Edward J. Septimus, MD; Karen L. Staman, MS; Miguel A. Vazquez, MD; William M. Vollmer, PhD; Douglas Zatzick, MD; Adrian F. Hernandez, MD, MHS; Richard Platt, MD, MS

Although the need to safeguard the confidentiality of patients whose data might be shared is widely recognized, the authors discuss the similar need to consider the risks to health care systems and physicians when the data from pragmatic clinical trials are shared.

Ann Intern Med. 2017;167(9):668-670. doi:10.7326/M17-0863

Holly M. Holmes, MD, MS; Greg A. Sachs, MD

The editorialists discuss Wouters and colleagues' study and highlight the important messages for clinicians who practice in nursing homes.

Ann Intern Med. 2017;167(9):671-672. doi:10.7326/M17-2268

E. Victor Adlin, MD

The editorialist discusses Brown and colleagues' study, noting that primary aldosteronism may occur frequently before development of hypertension and deserves more diagnostic attention than it now receives.

Ann Intern Med. 2017;167(9):673-674. doi:10.7326/M17-2237

Sanket S. Dhruva, MD; Jeptha P. Curtis, MD

The editorialists discuss the findings of Zhang and colleagues' systematic review in light of one company's recent announcement that it is halting sales of BVSs.

Ann Intern Med. 2017;167(9):675-676. doi:10.7326/M17-2522

Sheldon Greenfield, MD; Sherrie H. Kaplan, PhD, MPH

The editorialists discuss the synopsis of the joint U.S. Department of Veterans Affairs/U.S. Department of Defense guidelines on management of type 2 diabetes. They also explore the sources of conflicting guidelines and speculate that developing recommendations for prespecified patient risk groups could improve consensus.

Ann Intern Med. 2017;167(9):677-678. doi:10.7326/M17-2665

David J. Malebranche, MD, MPH

The heat was stifling in the clinic that morning, and the underachieving air conditioner didn't seem to care. A typical day in our community HIV center was unfolding like the train wreck it often was.

Ann Intern Med. 2017;167(9):679-680. doi:10.7326/M17-1916

Charlotte Grinberg, MD

I once heard a physician quote Maya Angelou: “I always remind myself that people aren't going to remember what you told them or how you told them, but they will remember how you made them feel.”

Ann Intern Med. 2017;167(9):681-682. doi:10.7326/M17-0429

Ann Intern Med. 2017;167(9):683-684. doi:10.7326/L17-0396

Ann Intern Med. 2017;167(9):684-686. doi:10.7326/M17-1408

Ann Intern Med. 2017;167(9):686. doi:10.7326/L17-0392

Ann Intern Med. 2017;167(9):687. doi:10.7326/L17-0393

Ann Intern Med. 2017;167(9):687-688. doi:10.7326/L17-0435

Ann Intern Med. 2017;167(9):688. doi:10.7326/L17-0436

Andrew S. Levey, MD; Matthew T. James, MD

Ann Intern Med. 2017;167(9):ITC66-ITC80. doi:10.7326/AITC201711070

Darren B. Taichman, MD, PhD

Ann Intern Med. 2017;167(9):ED9. doi:10.7326/AFED201711070

Darilyn V. Moyer, MD

Building on the popular Annals feature “On Being a Doctor,” storytellers share stories about the experience of doctoring on video. Here, Dr. Moyer relays her story of balancing doctoring and parenting.

Ann Intern Med. 2017;167(9):SS1. doi:10.7326/W17-0063

Carrie A. Horwitch, MD, MPH

Building on the popular Annals feature “On Being a Doctor,” storytellers share stories about the experience of doctoring on video. Here, Dr. Horwitch relays her story of balancing doctoring and parenting.

Ann Intern Med. 2017;167(9):SS1. doi:10.7326/W17-0064

Rebecca Masters, MD

Building on the popular Annals feature “On Being a Doctor,” storytellers share stories about the experience of doctoring on video. Here, Dr. Masters relays her story of balancing doctoring and parenting.

Ann Intern Med. 2017;167(9):SS1. doi:10.7326/W17-0065

Heather E. Gantzer, MD

Building on the popular Annals feature “On Being a Doctor,” storytellers share stories about the experience of doctoring on video. Here, Dr. Gantzer relays her story of balancing doctoring and parenting.

Ann Intern Med. 2017;167(9):SS1. doi:10.7326/W17-0066

Jacqueline W. Fincher, MD

Building on the popular Annals feature “On Being a Doctor,” storytellers share stories about the experience of doctoring on video. Here, Dr. Fincher relays her story of balancing doctoring and parenting.

Ann Intern Med. 2017;167(9):SS1. doi:10.7326/W17-0067

Susan Thompson Hingle, MD

Building on the popular Annals feature “On Being a Doctor,” storytellers share stories about the experience of doctoring on video. Here, Dr. Hingle relays her story of balancing doctoring and parenting.

Ann Intern Med. 2017;167(9):SS1. doi:10.7326/W17-0068

Ana Maria Lopez, MD, MPH

Building on the popular Annals feature “On Being a Doctor,” storytellers share stories about the experience of doctoring on video. Here, Dr. Lopez relays her story of balancing doctoring and parenting.

Ann Intern Med. 2017;167(9):SS1. doi:10.7326/W17-0069

Kyle Burch, BA

Laugh (or cry?) as what starts as a simple issue evolves into a complex medical problem list.

Ann Intern Med. 2017;167(9):W47-W52. doi:10.7326/G17-0007