Robert Belknap, MD; David Holland, MD, MHS; Pei-Jean Feng, MPH; Joan-Pau Millet, MD, MPH; Joan A. Caylà, MD, PhD; Neil A. Martinson, MBBCh, MPH; Alicia Wright, BS; Michael P. Chen, PhD; Ruth N. Moro, MD, MPH; Nigel A. Scott, MS; Bert Arevalo, BS, CCRP; José M. Miró, MD, PhD; Margarita E. Villarino, MD, MPH; Marc Weiner, MD; Andrey S. Borisov, MD, MPH; for the TB Trials Consortium iAdhere Study Team
Expanding latent tuberculosis treatment is important to decrease active disease globally. This study compared treatment completion and safety of self-administered once-weekly isoniazid and rifapentine versus direct observation.
Ann Intern Med. 2017;167(10):689-697. doi:10.7326/M17-1150
Òscar Miró, PhD; Xavier Rossello, MD; Víctor Gil, PhD; Francisco Javier Martín-Sánchez, PhD; Pere Llorens, PhD; Pablo Herrero-Puente, PhD; Javier Jacob, PhD; Héctor Bueno, PhD; Stuart J. Pocock, PhD; on behalf of the ICA-SEMES Research Group
The emergency department (ED) plays a central role in the management of acute heart failure, but emergency physicians require additional tools to stratify patients by risk. In this prospective cohort study involving patients from 34 EDs in Spain, the authors sought to develop a model that could predict mortality using data that are readily available at ED admission.
Ann Intern Med. 2017;167(10):698-705. doi:10.7326/M16-2726
Jose F. Figueroa, MD, MPH; Karen E. Joynt Maddox, MD, MPH; Nancy Beaulieu, PhD; Robert C. Wild, MS, MPH; Ashish K. Jha, MD, MPH
Finding areas of care where we can save money and improve quality has proved difficult. One approach has focused on high-need, high-cost patients. However, we know little about how much of the spending for these patients is preventable. Therefore, this study sought to identify preventable spending in clinically distinct subpopulations of high-cost patients, to identify care settings where preventable spending is more likely to occur, and to identify specific types of hospitalizations that drive preventable spending.
Ann Intern Med. 2017;167(10):706-713. doi:10.7326/M17-0767
Kalyani Sonawane, PhD; Ryan Suk, MS; Elizabeth Y. Chiao, MD, MPH; Jagpreet Chhatwal, PhD; Peihua Qiu, PhD; Timothy Wilkin, MD, MPH; Alan G. Nyitray, PhD; Andrew G. Sikora, MD, PhD; Ashish A. Deshmukh, PhD, MPH
The prevalence of human papillomavirus (HPV)–positive oropharyngeal cancer is disproportionately high among men. Data from the National Health and Nutritional Examination Survey (2011 to 2014) were used to determine the prevalence of oral HPV infection and the concordance of oral and genital HPV infection among U.S. men and women. This information is critical for designing detection and prevention efforts.
Ann Intern Med. 2017;167(10):714-724. doi:10.7326/M17-1363
Jason A. Nieuwsma, PhD; John W. Williams Jr., MD, MHSc; Natasha Namdari, MD; Jeffrey B. Washam, PharmD; Giselle Raitz, MD; James A. Blumenthal, PhD; Wei Jiang, MD; Roshini Yapa, MBBS; Amanda J. McBroom, PhD; Kathryn Lallinger, MSLS; Robyn Schmidt, BA; Andrzej S. Kosinski, PhD; Gillian D. Sanders, PhD
This systematic review addresses the identification and treatment of depression in patients who have recently had an acute coronary syndrome event.
Ann Intern Med. 2017;167(10):725-735. doi:10.7326/M17-1811
Neal L. Benowitz, MD
In late July 2017, the U.S. Food and Drug Administration announced a new plan for tobacco regulation that focuses on regulating nicotine itself to reduce the nicotine content of cigarettes to nonaddictive levels. This commentary discusses the rationale behind this move and the promise it holds for reducing premature deaths from smoking combustible cigarettes.
Ann Intern Med. 2017;167(10):736-737. doi:10.7326/M17-2071
Helen W. Boucher, MD; Barbara E. Murray, MD; William G. Powderly, MD
Increasing resistance to antimicrobial agents has led to international pledges to increase funding for public health initiatives as well as for research and development to combat this grave threat. The authors discuss their views of the probable effect of proposals by the Trump administration on these efforts and on the leadership role of the United States in antimicrobial stewardship.
Ann Intern Med. 2017;167(10):738-739. doi:10.7326/M17-1678
Yumi T. DiAngi, MD; Tzielan C. Lee, MD; Christine A. Sinsky, MD; Bryan D. Bohman, MD; Christopher D. Sharp, MD
Myriad financial, quality, and service metrics pervade the professional lives of ambulatory care providers. These include measurements from the electronic health record (EHR), which include practice efficiency scores that create a window on the clinician's workflow. In this article, the authors propose a set of EHR-related metrics that provide further insight into the clinician experience.
Ann Intern Med. 2017;167(10):740-741. doi:10.7326/M17-0658
Haileyesus Getahun, MD; Alberto Matteelli, MD
Belknap and colleagues report a multisite randomized clinical trial that showed—in the 9 U.S. sites but not the South African site—similar completion rates for directly observed and self-administered weekly treatment. The editorialists discuss these findings and the importance of tailoring treatment of latent tuberculosis to individual patient circumstances.
Ann Intern Med. 2017;167(10):742-743. doi:10.7326/M17-2639
Peter S. Rahko, MD
Miró and colleagues report the development of a tool to predict 30-day mortality in patients with acute heart failure presenting to the ED. The editorialist discusses the findings and notes the need to test the performance of this and other models in diverse populations, which could guide development of an infrastructure to successfully identify patients who can be safely treated out of the hospital.
Ann Intern Med. 2017;167(10):744-745. doi:10.7326/M17-2389
Bruce Leff, MD; Arnold Milstein, MD
Figueroa and colleagues' finding that potentially preventable health care spending is highly concentrated among frail elderly persons resonates with the experience of clinicians. The editorialists discuss the findings in light of the shift in health care culture toward value-based care under the Patient Protection and Affordable Care Act.
Ann Intern Med. 2017;167(10):746-747. doi:10.7326/M17-2627
Patti E. Gravitt, PhD, MS
Sonawane and colleagues used data from the National Health and Nutrition Examination Survey (2011 to 2014) to analyze differences between men and women in the prevalence of oral HPV infection and the concordance of oral and genital HPV infection. Here, the editorialist discusses the study's findings and why standard epidemiologic analyses are fraught with inferential limitations.
Ann Intern Med. 2017;167(10):748-749. doi:10.7326/M17-2628
Karina W. Davidson, PhD, MASc; Lauren T. Wasson, MD, MPH; Ian M. Kronish, MD, MPH
Nieuwsma and colleagues' systematic review summarizes the evidence for the diagnostic accuracy of depression screening tests and management strategies for patients with acute coronary syndrome. The editorialists discuss the evidence gaps that must be filled to determine whether depression screening and management not only improves depression and quality of life in these patients but also enhances their chances of survival.
Ann Intern Med. 2017;167(10):750-751. doi:10.7326/M17-2831
Sergio Waxman, MD, MBA
Ann Intern Med. 2017;167(10):752. doi:10.7326/M17-0175
Ann Intern Med. 2017;167(10):753-755. doi:10.7326/M17-0711
Ann Intern Med. 2017;167(10):755-757. doi:10.7326/M17-1495
Ann Intern Med. 2017;167(10):757-758. doi:10.7326/L17-0437
Ann Intern Med. 2017;167(10):758-759. doi:10.7326/L17-0438
Ann Intern Med. 2017;167(10):759-760. doi:10.7326/L17-0476
Ann Intern Med. 2017;167(10):760. doi:10.7326/L17-0477
Ann Intern Med. 2017;167(10):JC50. doi:10.7326/ACPJC-2017-167-10-050
Ann Intern Med. 2017;167(10):JC51. doi:10.7326/ACPJC-2017-167-10-051
Ann Intern Med. 2017;167(10):JC52. doi:10.7326/ACPJC-2017-167-10-052
Ann Intern Med. 2017;167(10):JC53. doi:10.7326/ACPJC-2017-167-10-053
Ann Intern Med. 2017;167(10):JC54. doi:10.7326/ACPJC-2017-167-10-054
Ann Intern Med. 2017;167(10):JC55. doi:10.7326/ACPJC-2017-167-10-055
Ann Intern Med. 2017;167(10):JC56. doi:10.7326/ACPJC-2017-167-10-056
Ann Intern Med. 2017;167(10):JC57. doi:10.7326/ACPJC-2017-167-10-057
Ann Intern Med. 2017;167(10):JC58. doi:10.7326/ACPJC-2017-167-10-058
Ann Intern Med. 2017;167(10):JC59. doi:10.7326/ACPJC-2017-167-10-059
Geno J. Merli, MD; Howard H. Weitz, MD
Howard and Geno (the Consult Guys) help decide whether a procedure requiring anesthesia may proceed after a patient drank a cappuccino.
Ann Intern Med. 2017;167(10):CG1. doi:10.7326/W17-0011
Darren B. Taichman, MD, PhD
Ann Intern Med. 2017;167(10):ED10. doi:10.7326/AFED201711210
David H. Wesorick, MD; Vineet Chopra, MD, MSc
Ann Intern Med. 2017;167(10):HO1. doi:10.7326/AFHO201711210
Claire M. Rickard, RN, PhD; Nicole M. Marsh, RN, MAppPrac (HealthRes)
The peripheral intravenous catheter (PIVC) is one of the most important and prevalent medical devices in the hospital. However, these catheters have received limited attention in the realms of patient safety and health care quality. Although central venous catheters (CVCs) have garnered tremendous attention, the 3 million CVCs placed in the United States each year is dwarfed by 350 million PIVCs. Why have we paid so little attention to these devices?
Ann Intern Med. 2017;167(10):HO2-HO3. doi:10.7326/M17-2771
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