Peter P. Reese, MD, MSCE; Peter L. Abt, MD; Emily A. Blumberg, MD; Vivianna M. Van Deerlin, MD, PhD; Roy D. Bloom, MD; Vishnu S. Potluri, MD, MPH; Matthew Levine, MD, PhD; Paige Porrett, MD, PhD; Deirdre Sawinski, MD; Susanna M. Nazarian, MD, PhD; Ali Naji, MD, PhD; Richard Hasz, BS, MFS; Lawrence Suplee, MS; Jennifer Trofe-Clark, PharmD; Anna Sicilia, BS; Maureen McCauley, BA; Caren Gentile, MS; Jennifer Smith, BS; Bijan A. Niknam, BS, BA; Melissa Bleicher, MD; K. Rajender Reddy, MD; David S. Goldberg, MD, MSCE
Recent trials have found favorable short-term results with transplant of hepatitis C virus (HCV)–infected kidneys into HCV-negative recipients, but intermediate-term end points, such as durable HCV cure and 1-year graft function, remain unknown. The authors conducted a single-center, open-label, nonrandomized trial to describe 12-month HCV treatment outcomes, estimated glomerular filtration rate, and quality of life for 20 HCV-negative kidney transplant recipients.
Ann Intern Med. 2018;169(5):273-281. doi:10.7326/M18-0749
Salomeh Keyhani, MD, MPH; Stacey Steigerwald, MSSA; Julie Ishida, MD, MAS; Marzieh Vali, MS; Magdalena Cerdá, DrPH; Deborah Hasin, PhD; Camille Dollinger, BS; Sodahm R. Yoo, BS; Beth E. Cohen, MD, MAS
Although evidence is limited regarding the potential health benefits and safety of marijuana, legal access to it is increasing and marijuana products are being aggressively marketed to the public. This nationally representative U.S. survey evaluated public perceptions regarding the health benefits and risks of marijuana use.
Ann Intern Med. 2018;169(5):282-290. doi:10.7326/M18-0810
Pauline Raaschou, MD, PhD; Jonas Söderling, MSE, PhD; Carl Turesson, MD (Professor); Johan Askling, MD (Professor); for the ARTIS Study Group
Clinical guidelines have issued cautions about use of tumor necrosis factor inhibitors (TNFi) in patients with a history of cancer because these drugs may have tumor-promoting effects. Thus, use of TNFi in patients with rheumatoid arthritis and a history of cancer is a clinical conundrum. This population-based cohort study from Sweden examined the risk for cancer recurrence in patients with rheumatoid arthritis and a history of cancer who were prescribed TNFi.
Ann Intern Med. 2018;169(5):291-299. doi:10.7326/M17-2812
Rebecca O'Brien, MD; Eric Johnson, MS; Sebastien Haneuse, PhD; Karen J. Coleman, PhD; Patrick J. O'Connor, MD, MA, MPH; David P. Fisher, MD; Stephen Sidney, MD, MPH; Andy Bogart, MS; Mary Kay Theis, MA, MS; Jane Anau, BS; Emily B. Schroeder, MD, PhD; David Arterburn, MD, MPH
Bariatric surgery results in improved glycemic control in patients with type 2 diabetes mellitus and severe obesity, but whether it affects incidence of microvascular disease is uncertain. This long-term observational study compares the incidence of diabetic retinopathy, nephropathy, and neuropathy in severely obese patients with type 2 diabetes who either had bariatric surgery or received usual medical care.
Ann Intern Med. 2018;169(5):300-310. doi:10.7326/M17-2383
Heidi D. Nelson, MD, MPH; Amy Cantor, MD, MPH; Miranda Pappas, MA; Liev Miller, BA
This systematic review addresses evidence for the Women's Preventive Services Initiative recommendation for screening for urinary incontinence in women.
Ann Intern Med. 2018;169(5):311-319. doi:10.7326/M18-0225
Nancy O'Reilly, MHS; Heidi D. Nelson, MD, MPH; Jeanne M. Conry, MD, PhD; Jennifer Frost, MD; Kimberly D. Gregory, MD, MPH; Susan M. Kendig, JD, WHNP-BC; Maureen Phipps, MD, MPH; Alina Salganicoff, PhD; Diana Ramos, MD, MPH; Christopher Zahn, MD; Amir Qaseem, MD, PhD, MHA; for the Women's Preventive Services Initiative
This article reports the Women's Preventive Services Initiative recommendations on screening for urinary incontinence in women.
Ann Intern Med. 2018;169(5):320-328. doi:10.7326/M18-0595
Benjamin E. Berkman, JD, MPH; Wynter K. Miller, JD; Christine Grady, RN, PhD
Information from online genealogy services might be used in manners not anticipated by consumers, including as forensic evidence in crime solving. The authors discuss the informed consent, privacy, and justice issues of such use.
Ann Intern Med. 2018;169(5):333-334. doi:10.7326/M18-1348
Sandra A. Springer, MD; P. Todd Korthuis, MD, MPH; Carlos del Rio, MD
In this article, the authors discuss 5 action steps from a recent workshop on the integration of infectious disease considerations and responses to the opioid use disorder epidemic.
Ann Intern Med. 2018;169(5):335-336. doi:10.7326/M18-1203
Daniel S. Graciaa, MD, MPH; Matthew H. Collins, MD, PhD; Henry M. Wu, MD
Many gaps in our knowledge about key features of Zika virus infection make it difficult to counsel patients who are contemplating travel to Zika-affected countries and to determine appropriate testing strategies on their return. The authors suggest an approach to shared decision making between travel medicine providers and patients.
Ann Intern Med. 2018;169(5):337-338. doi:10.7326/M18-1112
Lisa S. Rotenstein, MD, MBA; Rebecca A. Berman, MD; Joel T. Katz, MD; Maria A. Yialamas, MD
Female physicians are less likely to become full professors and are paid lower salaries than their male colleagues. This article describes the discovery of a gender disparity in “shout-outs” in a residency program and actions that rectified the disparity.
Ann Intern Med. 2018;169(5):339-340. doi:10.7326/M18-1118
Joel Tsevat, MD, MPH; Christopher Moriates, MD
Value-based health care (VBHC), cost-effectiveness analysis, and value-based payment (a component of VBHC) are 3 approaches for addressing “bang for the health care buck.” In this article, the authors compare these approaches to efficient resource allocation and emphasize the need for them to better align in order to provide the best possible care at the lowest possible costs for patients.
Ann Intern Med. 2018;169(5):329-332. doi:10.7326/M18-0342
Adnan Sharif, MBChB, MD
Reese and colleagues provided evidence for the benefits of transplanting HCV–positive kidneys into HCV-negative recipients in the current era of direct-acting antiviral agents. The editorialist discusses the promise these results present for improving outcomes for patients requiring kidney transplant.
Ann Intern Med. 2018;169(5):341-342. doi:10.7326/M18-1781
Carel W. le Roux, MD, PhD; Philip R. Schauer, MD
O'Brien and colleagues investigated the relationship between bariatric surgery and incident microvascular complications of type 2 diabetes mellitus. The editorialists discuss the findings and why they believe that bariatric surgery is safe and is, at present, our most evidence-based treatment to put hyperglycemia into remission.
Ann Intern Med. 2018;169(5):343-344. doi:10.7326/M18-2114
Robin J. Bell, MBBS, PhD, MPH; Susan R. Davis, MBBS, PhD
The editorialists discuss recommendations from the Women's Preventive Services Initiative on screening for urinary incontinence in women and advise caution regarding widespread screening on the basis of limited, indirect evidence.
Ann Intern Med. 2018;169(5):345-346. doi:10.7326/M18-1768
Maria Maldonado, MD
Ann Intern Med. 2018;169(5):347-348. doi:10.7326/M18-0782
Michael M. Danielson; Karine Dubé, DrPH
Ann Intern Med. 2018;169(5):349. doi:10.7326/M18-1719
Ann Intern Med. 2018;169(5):350-352. doi:10.7326/M17-2930
Ann Intern Med. 2018;169(5):352-353. doi:10.7326/L17-0759
Ann Intern Med. 2018;169(5):353-354. doi:10.7326/L18-0246
Ann Intern Med. 2018;169(5):354. doi:10.7326/L18-0247
Ann Intern Med. 2018;169(5):354. doi:10.7326/L18-0294
Ann Intern Med. 2018;169(5):355. doi:10.7326/L18-0295
Ann Intern Med. 2018;169(5):355-356. doi:10.7326/L18-0312
Ann Intern Med. 2018;169(5):356. doi:10.7326/L18-0313
Houman Homayoun, MD
Ann Intern Med. 2018;169(5):ITC33-ITC48. doi:10.7326/AITC201809040
Darren B. Taichman, MD, PhD
Ann Intern Med. 2018;169(5):ED5. doi:10.7326/AFED201809040
Robert M. Centor, MD; Victor M. Montori, MD, MSc
In this episode of Annals On Call, Dr. Centor discusses guidelines regarding targets for glycemic control targets for patients with type 2 diabetes and the controversy around these recommendations.
Ann Intern Med. 2018;169(5):OC1. doi:10.7326/A18-0003
William J. Doan, BA, MFA, PhD
Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.
Ann Intern Med. 2018;169(5):W13-W29. doi:10.7326/G17-0020
Ann Intern Med. 2018;169(5):I-26. doi:10.7326/P18-0005
Ann Intern Med. 2018;169(5):I-22. doi:10.7326/P18-0011
Ann Intern Med. 2018;169(5):I-18. doi:10.7326/P18-0012
Ann Intern Med. 2018;169(5):I-12. doi:10.7326/P18-0013
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