Issues

Calvin Ke, MD; Eric Lau, PhD; Baiju R. Shah, MD, PhD; Thérèse A. Stukel, PhD; Ronald C. Ma, MB BChir; Wing-Yee So, MBChB, MD; Alice P. Kong, MD; Elaine Chow, MBChB, PhD; Philip Clarke, PhD; William Goggins, ScD; Juliana C.N. Chan, MBChB, MD; Andrea Luk, MBChB, MD

Type 2 diabetes (T2D) increases hospitalization risk. Young-onset T2D (defined as onset before age 40 years) is associated with excess morbidity and mortality, but its effect on hospitalizations is unknown. In this population-based cohort study, the authors examined 2 large cohorts of Chinese adults with T2D to determine the effects of age at onset and modifiable risk factors on hospitalization during the working lifespan.

Ann Intern Med. 2019;170(3):145-154. doi:10.7326/M18-1900

Michael Fralick, MD, SM; Seoyoung C. Kim, MD, ScD, MSCE; Sebastian Schneeweiss, MD, ScD; Dae Kim, MD, ScD; Donald A. Redelmeier, MD, MSc; Elisabetta Patorno, MD, DrPH

Canagliflozin, a sodium–glucose cotransporter-2 inhibitor used for diabetes treatment, has been associated with decreased bone mineral density, potentially increasing risk for fracture. This analysis examined risk for nonvertebral fractures among new users of canagliflozin compared with a glucagon-like peptide-1 agonist.

Ann Intern Med. 2019;170(3):155-163. doi:10.7326/M18-0567

W. Alton Russell, MS; Susan L. Stramer, PhD; Michael P. Busch, MD, PhD; Brian Custer, PhD

Universal individual donation nucleic acid testing (ID-NAT) of donated blood for Zika virus began in the United States and its territories in 2016. This microsimulation study estimated the effectiveness and cost-effectiveness of universal ID-NAT, universal mini-pool NAT, and alternative Zika virus screening policies in Puerto Rico and the 50 states.

Ann Intern Med. 2019;170(3):164-174. doi:10.7326/M18-2238

Anjala Tess, MD; Steven D. Freedman, MD, PhD; Tara Kent, MD; Howard Libman, MD

Acute pancreatitis is a common reason for hospitalization. Here, 2 experts debate how they would apply an American Gastroenterological Association guideline addressing management of acute pancreatitis to a patient with recurrent episodes, focusing on initial management and timing of subsequent surgery.

Ann Intern Med. 2019;170(3):175-181. doi:10.7326/M18-3536

David K. Kim, MD, MA; Paul Hunter, MD; on behalf of the Advisory Committee on Immunization Practices

This article provides immunization recommendations from the Advisory Committee on Immunization Practices (ACIP) for adults aged 19 years or older. The ACIP-recommended use of each vaccine is determined after in-depth reviews of vaccine-related data, including disease epidemiology and burden of disease, vaccine efficacy and effectiveness, vaccine safety, the quality of evidence, feasibility of program implementation, and economic analyses of immunization policy.

Ann Intern Med. 2019;170(3):182-192. doi:10.7326/M18-3600

Todd Cassese, MD; Melinda S. Sharkey, MD; Amber T. Pincavage, MD; Korry Schwanz, BA; Jeanne M. Farnan, MD, MHPE

The federal regulation regarding student documentation in the medical record was recently changed to allow the teaching physician to verify in the medical record any student documentation of evaluation and management services rather than redocumenting the work. This change will alter how students and teaching physicians interact and may have unintended consequences. This article describes some that should be avoided.

Ann Intern Med. 2019;170(3):193-194. doi:10.7326/M18-1924

E. Amy Janke, PhD; Caroline Richardson, MD; Kristin L. Schneider, PhD; on behalf of the Society of Behavioral Medicine Executive Committee

The 2017 hypertension guidelines from the American College of Cardiology and American Heart Association provide little guidance regarding specific lifestyle and behavioral approaches to prevent and manage hypertension. The goal of this essay is to increase physician awareness of the value and effectiveness of lifestyle interventions for managing hypertension as well as sources of practical, evidence-based information on implementing these strategies in the clinical setting.

Ann Intern Med. 2019;170(3):195-196. doi:10.7326/M18-2361

Renee N. Salas, MD, MPH, MS; Francine Laden, ScD; Wendy B. Jacobs, JD; Ashish K. Jha, MD, MPH

The U.S. Environmental Protection Agency has proposed requiring that data considered when making public policy be “publicly available” and “transparent.” The authors discuss the implications of this proposed rule, its intention, and what effect it could have on environmental protection and public health.

Ann Intern Med. 2019;170(3):197-198. doi:10.7326/M18-2673

Mary E. Tinetti, MD; Ariel R. Green, MD, MPH; Jennifer Ouellet, MD; Michael W. Rich, MD; Cynthia Boyd, MD, MPH

Multimorbidity, the coexistence of multiple chronic conditions, is common among all adults receiving health care and the norm among older adults. The authors discuss the limitations of disease-focused, guideline-based medication prescribing (and the randomized clinical trials that inform it) for older adults with multimorbidity and propose strategies to counteract these concerns.

Ann Intern Med. 2019;170(3):199-200. doi:10.7326/M18-3269

William D. Leslie, MD, MSc; John T. Schousboe, MD, PhD

The editorialists discuss Fralick and colleagues' findings and why they believe that real-world data are critical to pharmacovigilance.

Ann Intern Med. 2019;170(3):201-202. doi:10.7326/M18-3550

Katherine D. Ellingson, PhD; Matthew J. Kuehnert, MD

The editorialists discuss Russell and colleagues' results and the need to balance risk for Zika infection with costs of screening in light of the public's expectation of near-zero risk for transfusion-transmitted infection.

Ann Intern Med. 2019;170(3):203-204. doi:10.7326/M18-3527

Michael J. Green, MD, MS

This editorial discusses the 4 Annals Graphic Medicine comics published in this issue, which show the vulnerability that students feel during medical school.

Ann Intern Med. 2019;170(3):205-206. doi:10.7326/M18-3466

Richard B. Weinberg, MD

“I have come to thank you, doctor. I thank you so much. God has sent you to me.”

Ann Intern Med. 2019;170(3):207-208. doi:10.7326/M18-1604

Ann Intern Med. 2019;170(3):210-211. doi:10.7326/L18-0360

Ann Intern Med. 2019;170(3):211-213. doi:10.7326/L18-0358

Ann Intern Med. 2019;170(3):213-215. doi:10.7326/M18-1425

Ann Intern Med. 2019;170(3):215-216. doi:10.7326/L18-0602

Ann Intern Med. 2019;170(3):216. doi:10.7326/L18-0601

Ann Intern Med. 2019;170(3):216-217. doi:10.7326/L18-0604

Ann Intern Med. 2019;170(3):217. doi:10.7326/L18-0605

Ann Intern Med. 2019;170(3):217-218. doi:10.7326/L18-0610

Ann Intern Med. 2019;170(3):218-219. doi:10.7326/L18-0606

Ann Intern Med. 2019;170(3):218. doi:10.7326/L18-0608

Ann Intern Med. 2019;170(3):219. doi:10.7326/L18-0607

Ann Intern Med. 2019;170(3):219. doi:10.7326/L18-0609

Ann Intern Med. 2019;170(3):219-220. doi:10.7326/L18-0611

Ann Intern Med. 2019;170(3):220. doi:10.7326/L18-0691

Ann Intern Med. 2019;170(3):220. doi:10.7326/L18-0712

Kelly E. Largent, MD

Ann Intern Med. 2019;170(3):163. doi:10.7326/M18-1545

Alexandra Pârvan, PhD

Ann Intern Med. 2019;170(3):209. doi:10.7326/M18-2007

Elisabeth J. Woodhams, MD, MSc; Melissa Gilliam, MD, MPH

Ann Intern Med. 2019;170(3):ITC18-ITC32. doi:10.7326/AITC201902050

Darren B. Taichman, MD, PhD

Ann Intern Med. 2019;170(3):ED3. doi:10.7326/AWED201902050

Robert M. Centor, MD; Nancy A. Rigotti, MD

In this episode of Annals On Call, Dr. Centor discusses electronic cigarette use with Dr. Nancy Rigotti of Massachusetts General Hospital.

Ann Intern Med. 2019;170(3):OC1. doi:10.7326/A18-0013

Grace E. Farris, MD

“Dr. Mom” explores the challenges and ups and downs of juggling life as a hospitalist and mother. The feature appears monthly in Annals Graphic Medicine at Annals.org.

Ann Intern Med. 2019;170(3):W41-W42. doi:10.7326/G18-0042

Mollie Kotzen, MD, MPH

Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.

Ann Intern Med. 2019;170(3):W43-W53. doi:10.7326/G18-0006

Michelle Sayad, MD

Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.

Ann Intern Med. 2019;170(3):W54-W62. doi:10.7326/G18-0011

Shruti Sudhakar, MD

Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.

Ann Intern Med. 2019;170(3):W63-W67. doi:10.7326/G18-0013

Gazi M. Rashid, BS

Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.

Ann Intern Med. 2019;170(3):W68-W72. doi:10.7326/G18-0027