Dan Li, MD; Elizabeth Hoodfar, MS, LCGC; Sheng-Fang Jiang, MS; Natalia Udaltsova, PhD; Nhung P. Pham, MD; Yves Jodesty, MD; Mary Anne Armstrong, MA; Yun-Yi Hung, PhD; Robin J. Baker, MD; Debbie Postlethwaite, RNP, MPH; Uri Ladabaum, MD, MS; Theodore R. Levin, MD; Douglas A. Corley, MD, PhD; JoAnn Bergoffen, MD
Guidelines recommend screening all patients with newly diagnosed colorectal cancer (CRC) for Lynch syndrome (LS), but the efficiency of universal LS screening in elderly persons has not been well studied. In this retrospective cohort study in a large community-based health care system, the authors investigated the performance of CRC tumor–based LS screening among different age groups.
Lauren J. Ralph, PhD; Eleanor Bimla Schwarz, MD; Daniel Grossman, MD; Diana Greene Foster, PhD
This study examines the self-reported physical health of women who sought abortion over 5 years after either receiving or being denied abortion services. Although some argue that abortion is detrimental to women's health, these data provide evidence that suggest otherwise.
Jordana B. Cohen, MD, MSCE; Michael J. Lotito; Usha K. Trivedi, BS; Matthew G. Denker, MD, MSCE; Debbie L. Cohen, MD; Raymond R. Townsend, MD
This systematic review and meta-analysis examines cardiovascular and mortality risks associated with untreated white coat hypertension and treated white coat effect.
Amir Qaseem, MD, PhD, MHA; Devan Kansagara, MD, MCR; Jennifer S. Lin, MD, MCR; Reem A. Mustafa, MD, MPH, PhD; Timothy J. Wilt, MD, MPH; for the Clinical Guidelines Committee of the American College of Physicians*
The American College of Physicians (ACP) has been developing guidelines since 1981. ACP's Clinical Guidelines Committee, in collaboration with staff from the Clinical Policy department, develops clinical guidelines and guidance statements and continues to refine and enhance its methodology. This article presents an update of the methods used to develop ACP's clinical guidelines and guidance statements.
Keith D. Hentel, MD, MS; Andrew Menard, JD; John Mongan, MD; Jeremy C. Durack, MD; Pamela T. Johnson, MD; Ali S. Raja, MD, MBA, MPH; Ramin Khorasani, MD, MPH
Beginning 1 January 2020, providers ordering advanced imaging examinations (magnetic resonance imaging, computed tomography, and nuclear medicine studies) in outpatient and emergency department settings must use certified clinical decision support systems that meet approved appropriate use criteria as a prerequisite for payment for all patients covered by Medicare. This article explains the new regulations and program requirements.
Lisa H. Harris, MD, PhD; Vanessa Dalton, MD, MPH
In this issue, Ralph and colleagues compare long-term physical health outcomes between women who had an abortion and those who gave birth after being denied abortion care because of clinic gestational age limits. The editorialists discuss the findings and suggest that that the health of women may depend not only on not having a reason to seek abortion but also on being able to receive abortion should the need arise.
Daichi Shimbo, MD; Paul Muntner, PhD
Cohen and colleagues report a systematic review and meta-analysis that examines the associations between white coat hypertension and cardiovascular events and mortality. The editorialist discusses the findings, which provide contemporary data supporting U.S. and European guidelines that recommend out-of-office blood pressure monitoring.
Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.
Tamara Beetham, BA; Brendan Saloner, PhD; Sarah E. Wakeman, MD; Marema Gaye, MA; Michael L. Barnett, MD, MS
Despite increasing attention on opioid addiction and overdoses, most persons with opioid use disorder have not received care within the past year. This study assessed how often and how quickly callers posing as patients seeking care for heroin use were offered appointments by publicly listed buprenorphine prescribers.
David Paje, MD, MPH; Mary A.M. Rogers, PhD, MS; Anna Conlon, PhD; Scott A. Flanders, MD; Steven J. Bernstein, MD, MPH; Vineet Chopra, MD, MSc
Guidelines from professional societies recommend that clinicians avoid placing peripherally inserted central catheters (PICCs) in patients with chronic kidney disease (CKD). This study used data from a multi-institutional quality collaborative in Michigan on a sample of hospitalized patients who received PICCs to describe the frequency and characteristics of placement in patients with CKD.
Risa B. Burns, MD, MPH; Aria F. Olumi, MD; Douglas K. Owens, MD, MS; Gerald W. Smetana, MD
Prostate cancer screening is a contentious subject. In this session of Beyond the Guidelines, an internist and a urologist compare their approaches to prostate-specific antigen (PSA)-based screening for prostate cancer. This discussion includes their strategies for screening, the PSA threshold at which they recommend further diagnostic testing, and the role of shared decision making with the patient.
Philip J. Candilis, MD; Daniel T. Kim, MA, MPH; Lois Snyder Sulmasy, JD; for the ACP Ethics, Professionalism and Human Rights Committee
This position paper from the American College of Physicians, which is informed by an environmental scan of the literature, provides advice to clinicians and health care institutions on how to respond to physicians who may be impaired.
Jeffrey H. Samet, MD, MA, MPH; Jane Liebschutz, MD, MPH
In this issue, the American College of Physicians (ACP) provides recommendations on identifying, managing, and treating impaired physicians. The editorialists commend the ACP for addressing this difficult issue and setting forth principles to help guide all parties involved in the identification and management of physician impairment.
Pooja A. Lagisetty, MD, MSc; Amy Bohnert, PhD
Beetham and colleagues reported a “secret shopper” study that describes barriers patients face when seeking clinicians who provide buprenorphine treatment for opioid use disorders. The editorialists believe that the most pressing challenge is connecting patients to willing prescribers.
Marcia R. Silver, MD
In their article, Paje and colleagues report a study of peripherally inserted central catheter use in patients with chronic kidney disease (CKD). The editorialist discusses how vein protection depends on decision making by nonnephrologists caring for complex patients with CKD and the critical importance of education of the general medical community.
You've done this before: cared for women whose wishes were warped by politics.
Faith T. Fitzgerald, MD
Many years ago, San Francisco had a program where ambulances (unkindly called “boozer cruisers”) would set out at night to pick up people on the street. They were mostly alcoholics.
CaraBeth Lee, MD
Most wrenching of all is that he remembers his forgetting. The lonely terror to awaken each morning and inventory what's been taken, knowing that soon the vault may be empty.
Gaetan Sgro, MD
Darren B. Taichman, MD, PhD
Rocco Pallin, MPH; Sarabeth A. Spitzer, BA; Megan L. Ranney, MD, MPH; Marian E. Betz, MD, MPH; Garen J. Wintemute, MD, MPH
Robert M. Centor, MD; Ashita Tolwani, MD
In this episode of Annals On Call, Dr. Centor discusses the care of patients with acute kidney injury with Dr. Ashita Tolwani of University of Alabama at Birmingham.
Grace E. Farris, MD
Dr. Mom explores the challenges and ups and downs of juggling life as a hospitalist and mother. The feature appears monthly in Annals Graphic Medicine at Annals.org.
Jennifer L. Wolff, PhD; Lauren H. Nicholas, PhD; Amber Willink, PhD; John Mulcahy, MSPH; Karen Davis, PhD; Judith D. Kasper, PhD
In this observational study, based on the 2015 NHATS (National Health and Aging Trends Study) and linked Medicare claims, the authors sought to quantify differences in health care spending associated with adequate support for daily activities among community-living older adults with disability. The results provide evidence for how health care spending is affected by factors in the broader social environment beyond demographic characteristics, diseases, and function and also help to identify subgroups for which targeting of outreach efforts is most likely to be cost-saving.
David Blumenthal, MD; Melinda K. Abrams, MS
In their article, DesRoches and colleagues report data that suggest that patients' access to their physicians' visit notes may improve their adherence to medication regimens. The editorialists discuss the findings and share their belief that the question is no longer whether patients should have full access to their health records but how to ensure that shared health care information improves patient outcomes.
Michael D. George, MD, MSCE; Joshua F. Baker, MD, MSCE; Kevin Winthrop, MD, MPH; Evo Alemao, RPh, PhD; Lang Chen, PhD; Sean Connolly, PhD; Jesse Y. Hsu, PhD; Teresa A. Simon, MPH; Qufei Wu, MS; Fenglong Xie, MS; Shuo Yang, MS; Jeffrey R. Curtis, MD, MS, MPH
Patients, particularly those with rheumatoid arthritis (RA), are at increased risk for infection after major surgery. In this analysis, the authors examined risk for infection across different biologic medications and with exposure to glucocorticoids in a large sample of patients with RA who underwent a primary or revision total knee or hip arthroplasty.
Bheeshma Ravi, MD, PhD; Gillian Hawker, MD, MSc
In their article, George and colleagues report a cohort study that used administrative claims data to compare infection risk across biologic therapies in the setting of primary or revision hip or knee joint replacement surgery in adults with rheumatoid arthritis. The editorialists discuss the implications of the findings but note that this study does not resolve the question of whether withholding biologic therapies in the perioperative period reduces patients' overall risk for infection complications.
Bruce Baird Struminger, MD, MA; Sanjeev Arora, MD
In their brief research report, Drake and colleagues call needed attention to rural America's poor health care access with their exploration of broadband Internet availability. The editorialists discuss the findings and recommend strategies to increase telehealth access that go beyond improving Internet service.
M. Hong Nguyen, MD; Cornelius J. Clancy, MD; A. William Pasculle, ScD; Peter G. Pappas, MD; George Alangaden, MD; George A. Pankey, MD; Bryan H. Schmitt, DO; Altaf Rasool, MD; Melvin P. Weinstein, MD; Raymond Widen, MD; Diana R. Hernandez, PhD; Donna M. Wolk, PhD; Thomas J. Walsh, MD; John R. Perfect, MD; Mollie N. Wilson, MS; Eleftherios Mylonakis, MD
The T2Bacteria Panel is a direct-from-blood, nonculture test that detects 5 common bacterial pathogens. This multicenter study examines the performance of the test in diagnosing suspected bloodstream infections in hospitalized adults.
David A. Weinrib, MD; Gerald A. Capraro, PhD, D(ABMM)
In this issue, Nguyen and colleagues report on the performance of the T2Bacteria Panel, which combines polymerase chain reaction amplification and T2 magnetic resonance to identify 5 important pathogens: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Escherichia coli. The editorialists discuss the findings and the additional evidence that is needed to evaluate the clinical usefulness of the assay.
Joshua D. Wallach, MS, PhD; Harlan M. Krumholz, MD, SM
In their brief research report, Tatsioni and colleagues report the characteristics of large, registered, randomized controlled trials with long-unreported or unpublished results. The editorialists discuss the findings and believe that failure to report clinical trial results should be considered academic misconduct at the individual and institutional levels.
Howard A. Fink, MD, MPH; Roderick MacDonald, MS; Mary L. Forte, PhD, DC; Christina E. Rosebush, MPH; Kristine E. Ensrud, MD, MPH; John T. Schousboe, MD, PhD; Victoria A. Nelson, MSc; Kristen Ullman, MPH; Mary Butler, PhD, MBA; Carin M. Olson, MD, MS; Brent C. Taylor, MPH, PhD; Michelle Brasure, PhD, MSPH, MLIS; Timothy J. Wilt, MD, MPH
This systematic review of 48 studies examines the benefits and harms of long-term osteoporosis drug treatment, as well as the benefits and harms of treatment discontinuation and holidays.
Albert Siu, MD, MSPH; Heather Allore, PhD, MS, MA; Darryl Brown, PhD, MPA; Susan T. Charles, PhD; Matthew Lohman, PhD, MHS
In October 2018, the National Institutes of Health convened the Pathways to Prevention (P2P) Workshop: Appropriate Use of Drug Therapies for Osteoporotic Fracture Prevention to assess the available evidence on long-term use of drug therapies to prevent osteoporotic fractures and identify research gaps and needs for advancing the field. This final report summarizes the panel's findings and recommendations.
Carolyn J. Crandall, MD, MS
In this issue, Siu and colleagues summarize the October 2018 National Institutes of Health Pathways to Prevention Workshop on long-term drug therapy to prevent osteoporotic fracture, and Fink and colleagues report the systematic review that informed the workshop. The editorialist discusses the important gaps in our understanding of the long-term treatment of osteoporosis, where “long-term” is defined as longer than 3 years.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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