Best of Annals 2017
In 2017, Annals of Internal Medicine published a number of notable articles focused on timely, important issues facing physicians today. Here are a few of those articles; some you may have missed, some may be worth reading again.
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Health Policy Articles
ACP Clinical Guidelines
ACP Position Paper
Other Articles of Note
Reconciling the Effects of Screening on Prostate Cancer Mortality in the ERSPC and PLCO Trials
Two important prostate cancer screening trials provided compatible evidence that screening reduces prostate cancer mortality. These findings suggest that current guidelines recommending against routine PSA-based screening may be revised.
Breast Cancer Screening in Denmark: A Cohort Study of Tumor Size and Overdiagnosis
Breast cancer screening in Denmark was associated with a substantial increase in the incidence of nonadvanced tumors and DCIS but not with a reduction in the incidence of advanced tumors. The rate of overdiagnosis was also substantial.
Patterns of Sedentary Behavior and Mortality in U.S. Middle-Aged and Older Adults: A National Cohort Study
Excessive sedentary time is a significant risk factor for all-cause mortality, regardless of exercise habits. Taking movement breaks every 30 minutes throughout the day could help to mitigate the negative health effects of too much sitting.
Coffee Drinking and Mortality in 10 European Countries: A Multinational Cohort Study
Compared with noncoffee drinkers, those who consume the most coffee have a significantly lower risk for death. The study, conducted in 10 European countries, was the largest ever of its kind.
Prescription Opioid Use, Misuse, and Use Disorders in U.S. Adults: 2015 National Survey on Drug Use and Health
More than a third (91.8 million) of the U.S. adult population used prescription opioids, 11.5 million misused them, and 1.9 million had a use disorder, according to findings from a 2015 National Survey on Drug Use and Health.
Antibiotic Prescribing for Nonbacterial Acute Upper Respiratory Infections in Elderly Persons
Nearly 1 in 2 elderly patients who visited a primary care physician for a nonbacterial acute upper respiratory infection received an antibiotic, despite opposing advice from clinical guidelines.
The Effects of Cannabis Among Adults With Chronic Pain and an Overview of General Harms: A Systematic Review
Benefits and Harms of Plant-Based Cannabis for Posttraumatic Stress Disorder: A Systematic Review
These reviews found that the scientific evidence is too limited to make firm conclusions about the effectiveness and safety of cannabis and cannabinoid products in treating chronic pain or posttraumatic stress disorder.
The Impact of Whole-Genome Sequencing on the Primary Care and Outcomes of Healthy Adult Patients: A Pilot Randomized Trial
Whole-genome sequencing found risk for rare genetic disease in 1 out of 5 generally healthy patients in primary care. While some primary care physicians may be able to manage genomic information appropriately, findings could prompt increased health care use with limited clinical value.
Nicotine, Carcinogen, and Toxin Exposure in Long-Term E-Cigarette and Nicotine Replacement Therapy Users: A Cross-sectional Study
Smokers who quit may see a health benefit from switching to e-cigarettes.
Firearm Injury–Related Articles
Annals has published many commentaries and original research articles aimed at helping physicians better understand how to decrease firearm injury. A special collection of all gun-related Annals content is free to the public.
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